Search for dissertations about: "Kristin Karlsson"

Showing result 1 - 5 of 8 swedish dissertations containing the words Kristin Karlsson.

2. 1. Benefits of Pharmacometric Model-Based Design and Analysis of Clinical Trials

   Author : Kristin E Karlsson; E Niclas Jonsson; Mats O Karlsson; Anders Grahnén; Michael K Smith; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; model-based analysis; pharmacometrics; modeling; disease progression; NONMEM; SAEM; Importance sampling; repeated time-to-event; RTTCE; RCEpT; NIH stroke scale; Barthel index; internal validation; external validation; study power; study design; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Abstract : Quantitative pharmacokinetic-pharmacodynamic and disease progression models are the core of the science of pharmacometrics which has been identified as one of the strategies that can make drug development more effective. To adequately develop and utilize these models one needs to carefully consider the nature of the data, choice of appropriate estimation methods, model evaluation strategies, and, most importantly, the intended use of the model. READ MORE

4. 2. Characterisation of pollutants in stormwater treatment facilities

   Author : Kristin Karlsson; Davis Butler; Luleå tekniska universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VA-teknik; Urban Water Engineering;

   Abstract : The overall objective of this thesis is to increase the knowledge of both the pollutants within stormwater treatment facilities and the maintenance of these facilities. This objective has been achieved by studying water and sediment with respect to metal concentrations, fractionation, and toxicity from ponds, sedimentation tanks, and gully pots with different catchment characteristics as well as from the sediment removal process. READ MORE

5. 3. Pathways of pollutants in stormwater systems

   Author : Kristin Karlsson; Luleå tekniska universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VA-teknik; Urban Water Engineering;

   Abstract : The choice of stormwater procedures will affect the pathways of the water and its pollutants, since different stormwater facilities reduce different types of substances and fractions to varying degrees. Traditional stormwater handling has mainly been emphasised to transport the water from the cities. READ MORE

6. 4. Stereotactic body radiation therapy of lung tumours : clinical and dosimetric aspects

   Author : Kristin Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The general aim of this thesis was to increase the knowledge regarding some clinical and methodological aspects, relevant in view of toxicity as well as tumour control, in stereotactic body radiation therapy (SBRT) of lung tumours. In the first two studies, reirradiation and radiation-induced atelectasis were studied. READ MORE

7. 5. Open heart surgery and its consequences for well-being - the perspectives of patients, relatives and health care professionals

   Author : Ann-Kristin Karlsson; Göteborgs universitet; []
   Keywords : Open heart surgery; depressed mood; well-being; qualitative methods;

   Abstract : Introduction: Adjustment to open heart surgery (OHS) is complex and necessitates multidimensional explanations. The surgery does not always provide the desired outcome, which can contribute to reduced well-being among patients and their relatives. Health care professionals (HCPs) play an important role in detecting signs of reduced well-being. READ MORE