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Showing result 1 - 5 of 12 swedish dissertations matching the above criteria.

  2. 1. Interactions between rat hepatocytes, collagen and fibronectin in cell adhesion phenomena

    Author : Kristofer Rubin; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment

    Author : Tomas Friman; Christian Sundberg; Kristofer Rubin; Ulf Eriksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap;

    Abstract : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. READ MORE

  5. 3. Functional Studies of Collagen-Binding Integrins α2β1 and α11β1 : Interplay between Integrins and Platelet-Derived Growth Factor Receptors

    Author : Gunilla Grundström; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Integrins are heterodimeric cell surface receptors, composed of an α- and a β-subunit, which mediate cell-extracellular matrix (ECM) interactions. Integrins mediate intracellular signals in response to extracellular stimuli, and cooperate with growth factor and other cytokine receptors. READ MORE

  6. 4. Interactions between Malignant Keratinocytes and Fibroblasts : Studies in Head and Neck Squamous Cell Carcinoma

    Author : Malin Hakelius; Daniel Nowinski; Bengt Gerdin; Kristofer Rubin; Avni Abdiu; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coculture; extracellular matrix; interleukin-1 alpha; tumor stroma; differential gene regulation; innate response; Plastic Surgery; Plastikkirurgi;

    Abstract : Carcinoma growth requires a supportive tumor stroma. The concept of reciprocal interactions between tumor and stromal cells has become widely acknowledged and the connective tissue activation seen in the malignant process has been likened to that of a healing wound. READ MORE

  7. 5. Fibroblast Contractility in vivo and in vitro : Effects of Prostaglandins and Potential Role for Inner Ear Fluid Homeostasis

    Author : Anna-Karin Hultgård Ekwall; Kristofer Rubin; Helge Rask-Andersen; Bengt Rippe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Interstitial connective tissue; fibroblasts; prostaglandins; podoplanin; endolymph resorption; Ménière’s disease.; Biokemi; Biochemistry; Biokemi;

    Abstract : Fibroblasts continuously strive to organize and compact the surrounding extracellular matrix (ECM). Recent data suggest that this cellular contractility controls interstitial fluid homeostasis in loose connective tissues (CT). READ MORE