Search for dissertations about: "Kromatin"

Showing result 1 - 5 of 7 swedish dissertations containing the word Kromatin.

  2. 1. The role of chromatin in the induction and repair of DNA damage

    Author : Mats Ljungman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA damage; Chromatin; Kromatin; DNA;

    Abstract : The role of chromatin in the induction and repair of DNA damage has a dual nature.The constituent proteins of chromatin protect the DNA against the induction of DNAdamage, while at the same time they reduce the accessibility of DNA to repair enzymes. READ MORE

  4. 2. New regulators of xylem lignification in arabidopsis

    Author : Bernadette Sztojka; Hannele Tuominen; Simon Hawkins; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Xylem; lignin; Arabidopsis; secondary cell wall; transcriptional regulation; lignin-biosynthetic gene; S G lignin ratio;

    Abstract : The ability of land plants to grow upright, bear their own weight and withstand adverse environmental conditions is largely dependent on the secondary xylem tissues of the stem. The xylem cells acquire thick secondary cell walls which are composed of cellulose, hemicellulose and lignin. READ MORE

  5. 3. Nuclear mechanisms in cell death induced by HAMLET (human alpha-lactalbumin made lethal to tumour cells)

    Author : Caroline Düringer; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; virology; mykologi; bakteriologi; virologi; mycology; bacteriology; Microbiology; chromatin; histones; apoptosis; alpha-lactalbumin; programmed cell death;

    Abstract : HAMLET (human alpha-lactalbumin made lethal to tumour cells), a protein-lipid complex originally isolated from human milk, induces programmed cell death selectively in tumour cells. It consists of partially unfolded alpha-lactalbumin in complex with oleic acid. READ MORE

  6. 4. Spatial transcriptome and epigenome analysis with focus on prostate cancer

    Author : Maja Marklund; Joakim Lundeberg; Patrik Ståhl; Marc Friedländer; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial; Spatial Transcriptomics; Spatial ATAC; epigenomics; Biotechnology; Bioteknologi;

    Abstract : Each cancer is unique, and therefore the use of general treatments are often suboptimal. If we can understand the mechanisms of cancer development, we might be able to develop effective treatments tailored to each patient. Our bodies are complex three-dimensional structures and how things are organized correlate with proper functioning. READ MORE

  7. 5. Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain

    Author : Nina Rosenqvist; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; Neurology; neuropsychology; ChIP; rat; transgene; insulator; differentiation; GFP; lentivirus; DNA methylation; histone deacetylation; chromatin; expression; silencing; stem cell; progenitor; gene therapy; neurofysiologi; neuropsykologi; CNS; transplantation;

    Abstract : The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. READ MORE