Search for dissertations about: "LDLR"

Showing result 16 - 20 of 27 swedish dissertations containing the word LDLR.

  2. 16. Subtracted Approaches to Gene Expression Analysis in Atherosclerosis

    Author : Stina Boräng; KTH; []
    Keywords : Representational Difference Analysis; atherosclerosis; gene expression profiling;

    Abstract : Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. READ MORE

  4. 17. Studies on the molecular regulation of bile acids and lipoproteins in human liver

    Author : Lisa-Mari Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Elevated lipid levels in the bloodstream, in particular high levels of LDL cholesterol, are a major risk factor for the development of atherosclerosis. The liver has a central role in cholesterol metabolism and is the only organ capable of a quantitative elimination of cholesterol from the body. READ MORE

  5. 18. Cardiac lipid storage and metabolism following myocardial ischemia

    Author : Christina Drevinge; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipid accumulation; Myocardial Ischemia; Lipid droplets; Perilipin2; Perilipin5;

    Abstract : Myocardial ischemia is associated with cellular- and metabolic adjustments within the heart, including accumulation of lipids. Myocardial lipids are stored in cytosolic droplets, consisting of a core of neutral lipids surrounded by a complex surface containing proteins, such as perilipins. READ MORE

  6. 19. The road from atherosclerosis to myocardial infarction : studies in an experimental model

    Author : Anne-Louise Hemdahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; myocardial infarction; ischemia; hypoxia; matrix metalloproteinase; remodelling; electrocardiogram; gene expression; inflammation;

    Abstract : Atherosclerosis is a slow progressing disease with continuous lipid deposition and inflammation in the arterial wall. Stenotic arteries may cause angina pectoris but it is the sudden formation of an occluding thrombosis on the atherosclerotic plaque that leads to myocardial infarction. READ MORE

  7. 20. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

    Author : Jeanna Perman; Göteborgs universitet; []
    Keywords : very low density lipoprotein receptor; lipid accumulation;

    Abstract : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. READ MORE