Search for dissertations about: "LLNA"

Found 5 swedish dissertations containing the word LLNA.

2. 1. Clinical and experimental studies on oxidized fragrance terpenes as contact allergens

   Author : Johanna Bråred Christensson; Göteborgs universitet; []
   Keywords : autoxidation; contact allergy; limonene; linalool; colophonium; limonene-1-hydroperoxide; limonene-2-hydroperoxide; 15-hydroperoxyabietic acid; 15-HPA; terpenes; local lymph node assay; LLNA; Freunds complete adjuvant test; FCAT; patch testing; laser Doppler imaging; skin irritation; visual reading;

   Abstract : The work presented in this thesis aims to improve the possibilities for diagnosing contact allergy to oxidized limonene and linalool and to, in patients, study contact allergy from structurally closely related hydroperoxides with regard to their specificity, potency and cross-reactivity. The fragrance terpenes limonene (from citrus oil) and linalool (from lavender oil) are widely used in household and industrial products. READ MORE

4. 2. Predictive testing for contact allergy : comparison of some guinea pig and mouse protocols including dose-response designs

   Author : Helen Wahlkvist; Karolinska Institutet; Karolinska Institutet; []
   Keywords : contact allergens; contact allergy; cumulative contact enhancement test; dose-response; evaluation; Freund s complete adjuvant test; guinea pig maximization test; local lymph node assay; mouse ear swelling test; patch test; predictive testing; statistical analysis;

   Abstract : Contact allergy (delayed hypersensitivity) may develop as a result of skin exposure to contact allergens (haptens) and can lead to allergic contact dermatitis. The purpose of this study was to evaluate some predictive animal test methods for contact allergens. READ MORE

5. 3. Analytical methodologies for common skin allergens : Organic thioureas, isothiocyanates and fragrance hydroperoxides in everyday life products

   Author : Ahmed Gamal Ramzi; Ulrika Nilsson; Anneli Julander; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemical analysis; contact allergy; chloroprene rubber; diethyl thiourea; ethyl isothiocyanate; fragrance hydroperoxides; Analytical Chemistry; analytisk kemi;

   Abstract : This thesis describes analytical methodologies for the determination of important skin-sensitizing chemicals in two types of commercial items: chloroprene rubber and fragrance products which are both well-known to be associated with contact allergy.Chloroprene rubber (neoprene) is widely used in different applications and products, such as bags, gloves, wetsuits, braces, mouse pads et c. READ MORE

6. 4. Limonene Hydroperoxides in Allergic Contact Dermatitis. Radical Formation, Sensitizing Capacity and Immunogenic Complex Formation

   Author : Staffan Johansson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; allergic contact dermatitis; contact allergy; immunogenic complex; limonene hydroperoxides; local lymph node assay; patch testing; radicals; sensitizing capacity; skin;

   Abstract : Contact allergy to fragrance compounds is an increasing problem in the western countries today. R-Limonene is one of the most common fragrance compounds; it is used in hygiene products and cosmetics as well as in industrial products such as hand cleansers and degreasers. READ MORE

7. 5. Chemical and Dermatological Aspects of UV-absorbing Compounds

   Author : Isabella Karlsson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Contact Allergy; Photoallergy; Dibenzoylmethane; Octocrylene; Ketoprofen; Scytonemin;

   Abstract : ABSTRACT The sun’s UV radiation is necessary for the existence of life on earth. However, too much UV exposure can lead to the development of skin cancer. Therefore, sunscreens are often used by the general population as protection from excessive UV radiation. READ MORE