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Showing result 1 - 5 of 22 swedish dissertations matching the above criteria.

  2. 1. Regulation of the Epstein-Barr Virus Latent Membrane Protein 1 Expression

    Author : Pegah Johansson; Göteborgs universitet; []
    Keywords : Gene regulation; LMP1; Epstein-Barr virus; Herpesvirus;

    Abstract : Epstein-Barr virus (EBV) is a probably the most effective and successful human virus, infecting more than 90% of the world?s adult population. As with the other members of the herpesvirus family, EBV establishes latent infection in its host and persists life-long. READ MORE

  4. 2. Transcriptional regulation of the latent membrane protein 1 gene by Epstein-Barr virus nuclear antigen 2

    Author : Lars Palmqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; EBNA2; transcription; phosphorylation; histone acetylation;

    Abstract : The Epstein-Barr virus (EBV) is a ubiquitous human herpes virus, which infects B-cells. This leads to a life-long latent infection, which in most cases is non-pathogenic. However, EBV is etiologically associated with several human malignancies, including endemic Burkitt's lymphoma, nasopharyngeal carcinoma and post-transplant lymphoma. READ MORE

  5. 3. Transcriptional regulation of the Epstein-Barr virus latent membrane protein 1 gene in B cells

    Author : Weiwen Yang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; LRS; EBNA2; transcription; transactivation; repression; histone deacytylation;

    Abstract : Epstein-Barr Virus (EBV) is a ubiquitous human B-lymphotrobic herpesvirus that latently infects over 90 percent of the world´s population. EBV infection is usually benign in healthy people. READ MORE

  6. 4. Nasopharyngeal carcinoma: past, present and future directions

    Author : Zahra Taheri-Kadkhoda; Göteborgs universitet; []
    Keywords : Nasopharyngeal carcinoma; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR.; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR;

    Abstract : Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients to identify key features for future improvements in patient care. READ MORE

  7. 5. Immunogenicity of and apoptosis modulation by Epstein-Barr virus (EBV)-encoded latent membrane protein-1 (LMP1) : implications for nasopharyngeal carcinoma

    Author : Xiangning Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus which infects more than 90% of individuals in the population, and has been shown to be associated with a variety of human tumors. The viral genome encodes a number of transforming proteins which enable the virus to efficiently immortalize B lymphocyte and also transform cells of other types. READ MORE