Search for dissertations about: "LRP"

Showing result 1 - 5 of 23 swedish dissertations containing the word LRP.

  2. 1. Small RNA-mediated Regulation of Gene Expression in Escherichia coli

    Author : Cecilia Unoson; E. Gerhart. H Wagner; Renée Schroeder; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Small RNA; non-coding RNA; antisense; translational control; ribosome standby; toxin-antitoxin; IstR; TisB; tisAB; MicF; Lrp; Microbiology; Mikrobiologi; Cell and molecular biology; Cell- och molekylärbiologi; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Non-coding RNAs are highly abundant regulators of gene expression in all kingdoms of life that often play important roles in vital cellular functions. In bacteria, small regulatory RNAs (sRNAs) usually act post-transcriptionally by regulating mRNAs through base pairing within ribosome binding sites (RBS), thereby inhibiting translation initiation. READ MORE

  4. 2. Transcription regulation and growth phase transition in hyperthermoacidophilic archaea

    Author : Kun Wang; Ann-Christin Lindås; Finn Werner; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Archaea; Sulfolobus; Transcription regulation; Lrp; TetR; BarR; ChIP-seq; RNA-seq; Transcriptome; growth phase transition; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Organisms from the domain Archaea are ubiquitously represented on our planet and encompass diverse fascinating organisms. The genus Sulfolobus belonging to the phylum Crenarchaeota including hyperthermoacidophilic strains that grow optimally at 65-85°C and pH 2-3. READ MORE

  5. 3. Experimental studies in brain tumours : with special regard to multidrug resistance and the ErbB-family

    Author : Ulrika Andersson; Roger Henriksson; Beatrice Malmer; Erik Blomquist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; glioma; meningioma; endothelium; MDR; Pgp; MRP1; LRP; MGMT; EGFR; ErbB2; ErbB3; ErbB4; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Abstract : Primary brain tumours, and especially the most common form malignant gliomas, usually display a pronounced resistance to other treatment modalities when surgery fails to cure. Growth factors, such as EGF and its receptor, frequently amplified and overexpressed in malignant gliomas, and factors associated with multidrug resistance have been suggested to at least partially explain the poor outcome. READ MORE

  6. 4. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs

    Author : Erik Holmqvist; E. Gerhart H. Wagner; Udo Bläsi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Small RNA; sRNA; non-coding RNA; antisense; gene regulation; post-transcriptional regulation; translational control; outer membrane protein; OmpA; MicA; biofilm; flagella; curli; bistability; Lrp; MicF; CsgD; FlgM; OmrA; OmrB; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. READ MORE

  7. 5. Experimental studies on multidrug resistance in human leukaemia : role of cellular heterogeneity for daunorubicin kinetics

    Author : Eva Knaust; Curt Peterson; Anna Porwit-MacDonald; Astrid Gruber; Christer Paul; Linköpings universitet; []
    Keywords : Acute myeloid leukaemia; heterogeneity; multidrug resistance. transport kinetics flow cytometry; gene expression; mdr1; mrp; lrp; apoptosis. bcl-2; p53; MEDICINE; MEDICIN;

    Abstract : Cellular resistance to chemotherapy is a major cause of treatment failure in acute myeloid leukaemia (AML) and still the majority of the patients die from their disease. Drug resistance 1s multifactorial, the most studied mechanism being multidrug resistance (MDR), mediated by the P-glycoprotein (Pgp). READ MORE