Search for dissertations about: "LRP1"

Showing result 1 - 5 of 9 swedish dissertations containing the word LRP1.

  2. 1. Mechanisms involved in macrophage phagocytosis of apoptotic cells

    Author : Anna Nilsson; Per-Arne Oldenborg; Karl-Eric Magnusson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; macrophages; dendritic cells; phagocytosis; apoptotic cells; senescent erythrocytes; CD47; SIRPalpha; LRP1; calreticulin; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. READ MORE

  4. 2. Periodontal medicine : oral inflammatory conditions with special emphasis on immunological aspects

    Author : Jeneen Panezai; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Systemic effects of periodontal disease have been a subject of interest for the past century, with intense focus converging since the past decade. Both rheumatoid arthritis (RA) and periodontal disease (PD) are immuno-inflammatory diseases with osteolysis as its hallmark feature. Activated T cells are known to modulate osteoclastogenesis. READ MORE

  5. 3. Heparan Sulfate in the Amyloidosis and Inflammation of Alzheimer’s Disease

    Author : Paul O'Callaghan; Xiao Zhang; Lars Lannfelt; Jeremy Turnbull; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; amyloidosis; amyloid-β; apolipoprotein E; astrocytes; glia; heparanase; heparan sulfate; heparan sulfate proteoglycans; microglia; neuroinflammation; Geriatrics; Geriatrik; Cellforskning; Cell Research; Neuroscience; Neurovetenskap; Pathology; Patologi;

    Abstract : Alzheimer’s disease (AD) is a neurodegenerative disorder, with extensive evidence implicating the misfolding, aggregation and deposition of the amyloid-β (Aβ) peptide as central to the pathogenesis. Heparan sulfate (HS) is an interactive glycosaminoglycan, attached to core proteins as HS proteoglycans (HSPGs). READ MORE

  6. 4. Asthma and allergy in teenagers and young adults, risk-factors and T-cell regulation

    Author : Sten-Erik Bergström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma is one of the most common chronic diseases among teenagers and young adults. The prevalence of asthma among young adults in Sweden is approximately 7-10%. Despite this, only a limited number of studies have focused on asthma, allergy and allergic inflammation in this age group. READ MORE

  7. 5. Novel factors affecting clearance of triacylglycerol-rich lipoproteins from blood

    Author : Stefan K Nilsson; Gunilla Olivecrona; Aivar Lookene; Ko Willems van Dijk; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipoprotein; triacylglycerol; apolipoprotein A-V; ANGPTL; Cardiovascular medicine; Kardiovaskulär medicin; medicinsk biokemi; Medical Biochemistry;

    Abstract : Apolipoprotein (apo) A-V is the most recently discovered member of a protein family responsible for the structure and metabolic fate of plasma lipoproteins. While most of the apolipoproteins are well characterized with regard to structure, interactions and function, the role of apoA-V is not well understood. READ MORE