Search for dissertations about: "LRT"

Showing result 1 - 5 of 7 swedish dissertations containing the word LRT.

2. 1. Methods for handling model misspecification in pharmacometric model-based approaches for the analysis of longitudinal clinical trial data

   Author : Estelle Chasseloup; Mats Karlsson; Andrew Hooker; Karl Brendel; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; nonlinear mixed-effects models; misspecification; type I error; power; accuracy; placebo; individual model averaging; IMA; likelihood ratio test; LRT; model averaging; covariate selection; mixture models; visual predictive checks; VPC; avatars; digital twins; virtual individual; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Pharmacometrics model-based analyses proved to be increasingly useful in drug discovery and development. This usefulness was made evident by the formalisation of the model-integrated drug discovery and development framework (MID3). READ MORE

4. 2. The effects of the land tenure reform programme on tenure security and agricultural development in Rwanda: the case of Musanze district, Northern Province

   Author : Emmanuel Muyombano; Göteborgs universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Land tenure systems; land administration; land management; land registration and titling; land use consolidation; land tenure security;

   Abstract : This PhD thesis is a compilation thesis comprising a research frame of seven chapters, and four related papers. The overall aim of this thesis is to investigate the effects of the land tenure reform programme on the livelihoods of small-scale farmers, focusing on two of the main components, the land registration and titling programme (LRT) and the land use consolidation (LUC) programme. READ MORE

5. 3. Preoperative radiotherapy in rectal cancer : aspects on fractionation and timing of surgery

   Author : Johan Erlandsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Neo-adjuvant radiotherapy (RT) in rectal cancer (RC) reduces the risk for local recurrence (LR). The optimal fractionation or time to surgery is not determined. The focus areas of this thesis are different RT-courses and timing of surgery in patients with RC. The Stockholm III trial forms the basis of the studies included in the thesis. READ MORE

6. 4. Modeling the global fate and transport of perfluoroalkylated substances (PFAS)

   Author : James M. Armitage; Ian T. Cousins; Michael S. McLachlan; David Ellis; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; perfluoroalkylated substances; global-scale; fate and transport; Environmental chemistry; Miljökemi; Applied Environmental Science; tillämpad miljövetenskap;

   Abstract : Perfluoroalkylated substances (PFAS) are persistent contaminants that are widely distributed in the global environment. Despite the fact that these chemicals have been manufactured and used for over 50 years, there has been little scientific and regulatory interest until very recently. READ MORE

7. 5. Elemental composition of fine particles: exposure in the general population and influence from different sources

   Author : Peter Molnár; Göteborgs universitet; []
   Keywords : particulate matter; PM2.5; PM1; ultrafine particles; trace elements; personal exposure; X-ray fluorescence XRF ; indoor levels; air mass back trajectories; long-range transport; domestic wood burning;

   Abstract : The general population is exposed to particulate air pollution from many different local and regional sources. Examples of local sources are traffic, biomass burning and resuspended dust, while regional sources are dominated by combustion processes from heating, traffic and industries. READ MORE