Search for dissertations about: "LTB4"

Showing result 1 - 5 of 44 swedish dissertations containing the word LTB4.

  2. 1. Development and application of monoclonal antibodies in studies of the human leukotriene B4 receptor, BLT1

    Author : Annika Pettersson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serologi; transplantation; Immunologi; Immunology; serology; antibodies; BLT1; LTB4;

    Abstract : Infection and inflammation are characterized by the release of chemotactic substances that activate cells of the immune system. One of these important mediators is LTB4, an arachidonic acid derivate that attracts e.g. monocytes and granulocytes to inflammatory sites and induces phagocytosis and degranulation. READ MORE

  4. 2. Innate defense mechanisms of the nasal airway

    Author : Henrik Widegren; Lund näs- och halssjukdomar Öron-; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Leukotriene B4; CC10; TNF-alpha; innate immunity; allergic rhinitis; Airway inflammation;

    Abstract : Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also causes exacerbations of asthma and chronic obstructive pulmonary disease. The immune mechanisms associated with various forms of rhinitis are not fully understood. READ MORE

  5. 3. Studies on leukotriene B4 and alarmins in inflammatory responses

    Author : Min Wan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator that is involved in host defense and inflammatory diseases, such as atherosclerosis. LL-37 and heparin binding protein (HBP) are cationic antimicrobial polypeptides, which belong to the alarmin family known to promote innate and adaptive immune reactions in response to tissue infection or injury. READ MORE

  6. 4. Proinflammatory factor mediated lymphocyte activation-the pivotal role of leukotriene B4

    Author : Anquan Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epstein-Barr virus (EBV) is ubiquitous in the human population. More than 90% of the individuals are virus carriers. The outcome of the first encounter with the virus is highly variable. It can occur unnoticed, but if infection is delayed until adolescence it causes the infectious mononucleosis syndrome in about half of the cases. READ MORE

  7. 5. Non-invasive analysis of leukotrienes as biomarkers of airway inflammation : method development and clinical applications

    Author : Flora Gaber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Airway inflammation; aspirin-intolerant asthma; biomarker; exhaled breath condensate; FENO; induced sputum; leukotrienes; 5-lipoxygenase; non-invasive analysis; saliva;

    Abstract : Asthma and chronic obstructive pulmonary disease (COPD) are two common diseases characterized by chronic airway inflammation, but the inflammation in asthma is different from the one in COPD. In addition, asthma is a heterogeneous disease presenting with many different phenotypes (e.g. READ MORE