Search for dissertations about: "LTNP"

Showing result 1 - 5 of 6 swedish dissertations containing the word LTNP.

  1. 1. Viral parameters influencing clinical long-term non progression in HIV-1 infected subjects

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Ubaldo Visco Comandini; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTNP; HIV-1 DNA; HIV-1 RNA; quantification; spontaneous decrease; genetic heterogeneity; nef; LTR; CCR5 deletion;

    Abstract : A very small portion of the HIV-1 infected population is constituted by individuals, called long- term non progressors (LTNP), in whom after even a decade or more, no visible deterioration of the immune system is recognized and the infection remains therefore asymptomatic. The reasons for such "natural" prolonged well-being can be attributed to both the virus and the infected host and their understanding is likely to give important information for the development of an effective HIV- vaccine and for immune reconstitution therapy. READ MORE

  2. 2. Slow progression in HIV-1 infection. : A clinical, virological and immunological study

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Christina Broström; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; PHI; prognosis; slow progression; LTNP; longitudinal; specific pattern; HIV-1 RNA; HIV-1 DNA; spontaneous decrease;

    Abstract : The aim of the present thesis was to study factors that could possibly influence the course of HIV- 1 infection with special emphasis on slow progression of the disease. Clinical, virological and immunological parameters were evaluated. One important clinical factor for the outcome of HIV-1 infection was identified. READ MORE

  3. 3. Virus tropism and neutralization response in SIV infection

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Anna Laurén; Lunds universitet.; Lund University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Natural science; Medicin människa och djur ; Medicine human and vertebrates ; HIV; SIV; mode of CCR5 use; CD4-independence; macrophage tropism; coreceptor use; neutralization; evolution; pathogenesis;

    Abstract : Popular Abstract in Swedish Sedan 1981, då de första fallen av AIDS beskrevs, har 25 miljoner människor dött på grund av att de har blivit smittade av immunbristviruset HIV . Det finns idag mer än 40 miljoner människor som lever med HIV eller AIDS. READ MORE

  4. 4. Regulation and role of IL-7 production in HIV-1 infection

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Hong Thang Pham; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The concentration of interleukin-7 (IL-7) in human serum is elevated in various clinical conditions associated with lymphopenia, including HIV-1 infection. IL-7 is an essential factor for T cell differentiation and survival, and it was suggested that high serum IL-7 concentration may represent a homeostatic response to T cell depletion, which may promote T cell regeneration. READ MORE

  5. 5. Leukemia inhibitor factor (LIF) and gp130 in early defence against HIV-1 infection

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Author : Annelie Tjernlund; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LIF; HIV-1; lymphoid tissue; cytokine; innate immune response; Jak Stat signalling pathway; cMAGI cells; siRNA;

    Abstract : Leukemia inhibitor factor (LIF) is a polyfunctional cytokine that belongs to the IL-6 family which mainly signals through the Jak/Stat pathway via the gp130/LIFR- heterodimer. The focus of my research has been to investigate and understand if and how LIF exerts HIV1 suppressing activity. READ MORE