Search for dissertations about: "LTP"

Showing result 1 - 5 of 35 swedish dissertations containing the word LTP.

  1. 1. Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms

    Author : Rui Li; Göteborgs universitet; []
    Keywords : synaptic plasticity; hippocampus; LTP; LTD; AMPA; NMDA; NR2A; NR2B;

    Abstract : Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric stimulation leading to activation of NMDA-R. READ MORE

  2. 2. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors

    Author : Yin-Ping Niu; Göteborgs universitet; []
    Keywords : learning and memory; synaptic plasticity; hippocampus; synapse; AMPA receptor; NMDA receptor; LTP; LTD; CV; TFS;

    Abstract : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). READ MORE

  3. 3. Activity-dependent changes of synaptic transmission in a long-term perspective and processes involved

    Author : Mikhail Dozmorov; Göteborgs universitet; []
    Keywords : synaptic plasticity; hippocampus; LTP; LTD; AMPA; NMDA; protein synthesis;

    Abstract : Synaptic plasticity is an essential property of the central nervous system. It is thought torepresent a mechanism for memory aquisition, storage and recall. The most well studied forms ofsynaptic plasticity are homosynaptic NMDAR-dependent LTP and LTD in the hippocampus inducedby specific patterns of electrical stimulation. READ MORE

  4. 4. Short- and long-term neuronal plasticity in hippocampal CA1 region of rat

    Author : Fen-Sheng Huang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glutamate; hippocampus; plasticity; synapse; LTP; LTD; AMPA; NMDA;

    Abstract : The brain is highly plastic, displaying both short- and long-term changes, resulting from developmental processes as well as learning and memory. Moreover, short-term plasticity such as paired pulse facilitation and depression (PPF, PPD) have long been used to monitor the presynaptic versus postsynaptic changes occurring during more lasting processes such as long-term potentiation and depression (LTP, LTD). READ MORE

  5. 5. Modeling receptor induced signaling in MSNs : Interaction between molecules involved in striatal synaptic plasticity

    Author : Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez-Arenas; Upinder S. Bhalla; Pierre Vincent; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatal synaptic plasticity; LTP; Dopamine; Acetylcholine; Synergy; Medium spiny neurons; MSNs;

    Abstract : Basal Ganglia are evolutionarily conserved brain nuclei involved in several physiologically important animal behaviors like motor control and reward learning. Striatum, which is the input nuclei of basal ganglia, integrates inputs from several neurons, like cortical and thalamic glutamatergic input and local GABAergic inputs. READ MORE