Search for dissertations about: "LTS"

Showing result 1 - 5 of 24 swedish dissertations containing the word LTS.

  2. 1. Computational Modelling and Topological Analysis of the striatal microcircuitry in health and Parkinson's disease

    Author : Ilaria Carannante; Jeanette Hellgren Kotaleski; Alexander Kozlov; Sean Hill; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Datalogi; Computer Science;

    Abstract : The basal ganglia are evolutionary conserved nuclei located at the base of the forebrain. They are a central hub in the control of motion and their dysfunctions lead to a variety of movement related disorders, including Parkinson's disease (PD).The largest nucleus and main input stage of the basal ganglia is the striatum. READ MORE

  4. 2. Automated Vulnerability Discovery and Attack Detection Framework for Cyber-Physical Systems

    Author : Fereidoun Moradi; Fereidoun Moradi; Sara Abbaspour Asadollah; Massimo Merro; Mälardalens universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Computer Science; datavetenskap;

    Abstract : The combination of physical assets with cyber computational entities, known as Cyber-Physical Systems (CPS), is becoming more common. These systems are used in various sectors such as manufacturing, energy production, and transportation. READ MORE

  5. 3. On striatum in silico

    Author : Johanna Frost Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The basal ganglia are a collection of subcortical nuclei involved in movement and action selection. The striatum is the main input nucleus with extensive projections from the cortex and thalamus, and dopaminergic projections from SNc and VTA. READ MORE

  6. 4. The enzymatic machinery of leukotriene biosynthesis : Studies on ontogenic expression, interactions and function

    Author : Tobias Strid; Sven Hammarström; Mats Söderström; Ralf Morgenstern; Linköpings universitet; []
    Keywords : ;

    Abstract : Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-lipoxygenase (5-LO) pathway. They are produced by myeloid cells. 5-LO converts AA to LTA4 in cooperation with 5-LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-hydrolase (LTA4H) or to LTC4 by LTC4-synthase (LTC4S). READ MORE

  7. 5. Extracellular vesicles : mediators of immune modulation in the lung and as therapeutic vehicles

    Author : Casper Ullsten-Wahlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Extracellular vesicles (EVs) are released from all cell types, and carry a wide setup of proteins, nucleic acids, lipids and other cargo. The overall aim of this thesis is to explore EV-based immune therapy, but also to find clues on mechanisms of the inflammatory disease sarcoidosis, and of lung cancer. READ MORE