Search for dissertations about: "Label-free enrichment"

Found 4 swedish dissertations containing the words Label-free enrichment.

  1. 1. Droplet microfluidics for single cell and nucleic acid analysis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Prem Kumar Periyannan Rajeswari; KTH.; [2016]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Biomarker detection; Cell behavior analysis; Cell factories; Droplet microfluidics; Droplet PCR; High throughput biology; Label-free enrichment; Single cell analysis; Biotechnology; Bioteknologi;

    Abstract : Droplet microfluidics is an emerging technology for analysis of single cells and biomolecules at high throughput. The controlled encapsulation of particles along with the surrounding microenvironment in discrete droplets, which acts as miniaturized reaction vessels, allows millions of particles to be screened in parallel. READ MORE

  2. 2. Single Molecule Detection Microfluidic Automation and Digital Quantification

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Malte Kühnemund; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE

  3. 3. Mass Spectrometry-based Neuroproteomics Deciphering the Human Brain Proteome

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sravani Musunuri; Uppsala universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Brain; Proteomics; Mass spectrometry; Alzheimer s disease; Traumatic brain injury; Membrane proteins; Sample preparation; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent advances in molecular imaging, genomics and proteomics have contributed significantly to achieve insights into molecular basis of brain function and pathogenesis of neurological disorders. READ MORE

  4. 4. Advances for Biomarker Discovery in Neuroproteomics using Mass Spectrometry From Method Development to Clinical Application

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marcus O.D. Sjödin; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Biomarker; Proteomics; Central Nervous System; Cerebrospinal Fluid; Traumatic Brain Injury; Cloud-Point Extraction; Neuroproteomics; Relative Quantification; Spinal Cord Stimulation; Neuropathic Pain; Analytical Chemistry; Analytisk kemi;

    Abstract : Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used as biomarkers for early diagnosis, assessing treatment or drug development. Clinical proteomics aim to screen for protein biomarkers by a comprehensive analysis of all proteins expressed in a biological matrix during a certain pathology. READ MORE