Search for dissertations about: "Lactadherin"

Showing result 1 - 5 of 6 swedish dissertations containing the word Lactadherin.

  2. 1. Medin amyloid - a matter close to the heart : Studies on medin amyloid formation and involvement in aortic pathology

    Author : Annika Larsson; Per Westermark; Sari Kiuru-Enari; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AA amyloidosis; aging; amyloid; aneurysm; arterial media; dissection; elastin; medin amyloid; lactadherin; thoracic aorta; Pathology; Patologi;

    Abstract : Amyloidoses are a group of protein misfolding diseases characterized by deposits of insoluble fibrillar protein aggregates. Medin amyloid, which is the focus of this thesis, appears in the media of the thoracic aorta in nearly all individuals over 50 years. READ MORE

  4. 2. Medin Amyloid in Human Arteries and its Association with Arterial Diseases

    Author : Siwei Peng; Per Wstermark; Gunnar Husby; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Amyloid; Medin; Lactadherin; Aneurysm; Aortic dissection; Temporal artery; Arteritis; Giant cell; Pre-aggregation.; Patologi; Pathology; Patologi;

    Abstract : Amyloid is a form of abnormal protein aggregation within the living body. Massive deposits can lead to organ failure. There is also increasing evidence that smaller pre-amyloid aggregates exert direct toxic effects to cells. READ MORE

  5. 3. Microvesicles, skin microcirculation and clinical microangiopathy in type 1 diabetes

    Author : Karin Bergen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Type 1 diabetes is a proinflammatory and prothrombotic disease associated with a highly elevated risk of microvascular complications, including nephropathy, retinopathy, and neuropathy, as well as premature cardiovascular disease. Aim: this thesis sought to study plasma microvesicles (MVs) and skin microcirculation in relation to clinical microangiopathy in type 1 diabetes, to try to identify potential clinical biomarkers. READ MORE

  6. 4. Studies of clinical and haemostatic features associated with antiphospholipid antibodies

    Author : Anna Vikerfors; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Antiphospholipid antibodies (aPL) are associated with a heterogeneous range of clinical conditions with predisposition for thrombosis, pregnancy morbidity and other autoimmune disorders, most frequently systemic lupus erythematosus (SLE). Both the clinical manifestations themselves and their treatment may be harmful to the affected individuals and aPL testing is still controversial. READ MORE

  7. 5. Apolipoprotein A-1 derived amyloid in the atherosclerotic intima of the human aorta

    Author : Gerd Mucchiano; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Amyloid is insoluble fibrillar protein deposited in the extracellular space. The resulting heterogeneous group of disorders, amyloidosis, can be sporadic or hereditary, and the amyloid is systemically distributed or localized in single organs. READ MORE