Search for dissertations about: "Laia Gorchs"

Found 1 swedish dissertation containing the words Laia Gorchs.

  1. 1. Cancer associated fibroblasts and T cells in pancreatic cancer : an immune perspective

    Author : Laia Gorchs; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : About 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC) and its deadly hallmarks, including a prominent fibrotic stroma, low mutational burden, lack of early diagnosis and rapid metastasis, contribute to trial failures and to the poor five-year overall survival rate of only 9%. Carcinoma associated fibroblasts (CAFs) are the most abundant cell type in the stroma of PDAC and their interactions with tumor cells leading to tumor progression have been extensively studied. READ MORE