Search for dissertations about: "Lamin A"
Showing result 1 - 5 of 16 swedish dissertations containing the words Lamin A.
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1. From nucleus to mitochondria : a ubiquitination study
Abstract : Ubiquitination is a post-translational modification achieved by an enzymatic cascade. This post-translational modification is involved in many crucial cellular processes across different cellular compartments such as protein turnover via the ubiquitin proteasome system and various signaling pathways from the DNA damage response to the immune response. READ MORE
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2. Autosomal Dominant Leukodystrophy with Autonomic Symptoms and Rippling Muscle Disease : Translational Studies of Two Neurogenetic Diseases
Abstract : There is a large variety of diseases caused by single-gene mutations. Although most of these conditions are rare, together they impose a significant burden to the population. READ MORE
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3. Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
Abstract : Hutchinson-Gilford progeria syndrome (HGPS) is a very rare genetic disease that presents some features of accelerated aging. Children with the disease are born appearing healthy but start to develop signs of the disease within their first years of life. READ MORE
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4. Apoptosis induced by a human milk protein complex. Cellular and structural studies in tumour cells and bacteria
Abstract : Human milk contains a vast array of bioactive molecules, with nutritional and protective functions. This thesis describes the effects of a human milk protein complex, MAL, on tumour cells and bacteria. During our studies on the anti-adhesive properties of human milk we observed that a milk fraction killed tumour cells. READ MORE
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5. The genetic mechanism that links Hutchinson-Gilford progeria syndrome to physiological aging
Abstract : Aging is a complex process that is not completely understood. The study of segmental progeroid syndromes such as Hutchinson-Gilford progeria syndrome (HGPS) has allowed us to connect the common genetic mechanisms that occur in normal physiological aging, with the cellular alterations presented by this severe premature aging syndrome. READ MORE