Search for dissertations about: "Lars Bohlin"

Showing result 6 - 10 of 20 swedish dissertations containing the words Lars Bohlin.

  2. 6. The Influence of Customer Agreements and Planning Principles on Rail Freight Performance

    Author : Lars Backåker; Lundgren Jan; Johanna Törnquist Krasemann; Stefan Engevall; Markus Bohlin; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rail freight planning; trip plan generation; routing and scheduling; dynamic assignment;

    Abstract : Rail freight transportation is recognized worldwide as a suitable transportation mode when it comes to long haul transportation of heavy commodities. The industry is also known to be capital intensive, highly dependent on infrastructural developments and requires thorough planning of operations. READ MORE

  4. 7. Capillary electrophoresis of 2-glycoprotein I: method development and binding studies

    Author : Lars G Blomberg; Maria E. Bohlin; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry;

    Abstract : .... READ MORE

  5. 8. Method development for affinity capillary electrophoresis of ß2-glycoprotein I and biological ligands

    Author : Maria E. Bohlin; Lars G Blomberg; Niels H H Heegaard; Jan Leo Reubsaet; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Capillary Electrophoresis; β2-glycoprotein I; acidic pretreatment; pH hysteresis effect; Affinity Capillary Electrophoresis; Kemi; Chemistry;

    Abstract : The final goal of this study is to establish a microscale analysis method that allows solution phase characterization of interactions between β2-glycoprotein I (β2gpI) and some of its ligands. Human β2gpI is a phospholipid- and heparin-binding plasma glycoprotein. READ MORE

  6. 9. Distribution and Chemical Diversity of Cyclotides from Violaceae : Impact of Structure on Cytotoxic Activity and Membrane Interactions

    Author : Robert Burman; Ulf Göransson; Lars Bohlin; William Gerwick; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclotide; Violaceae; Viola; Cytotoxic; Mechanism; In vivo; Structure-activity; Membrane; Mass spectrometry; Pharmacognosy; Farmakognosi; Pharmacognosy; Farmakognosi;

    Abstract : During the last decade there has been increased interest in the cyclotide protein family, which consist of a circular chain of approximately 30 amino acids, including six cysteines that form three disulfide bonds, arranged in a cyclic cystine knot motif. This thesis gives new insights in cyclotide distribution and occurrence in the plant family Violaceae, structure-activity relationships for cytotoxic effects, membrane disruption and adsorption on lipid membranes, and evaluates toxicity and anti-tumor activity in vivo. READ MORE

  7. 10. Studies of Cytotoxic Compounds of Natural Origin and their Mechanisms of Action

    Author : Jenny Felth; Lars Bohlin; Joachim Gullbo; Ulf Göransson; Thomas Efferth; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytotoxic; cardiac glycoside; gambogic acid; cancer; mechanism of action; Pharmacognosy; Farmakognosi; Pharmacognosy; Farmakognosi;

    Abstract : Cancer incidence is increasing and novel anticancer drugs with new mechanisms of action are essential for future chemotherapeutic treatment. Natural products have historically played an important role in the development of anti-cancer drugs and have potential to do so also in the future. READ MORE