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Found 3 swedish dissertations matching the above criteria.

  1. 1. Helicobacter pylori and Gastric Protection Mechanisms : An in vivo Study in Mice and Rats

    Author : Johanna Henriksnäs; Lena Holm; Lars Engstrand; Erik Persson; Lars Fändriks; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; mucus gel layer; mucosal blood flow; mucus thickness; intra-vital microscopy; laser-Doppler flowmetry; pH-sensitive microelectrode; nitric oxide; Helicobacter pylori; bicarbonate secretion; mouse model; Fysiologi; Physiology; Fysiologi;

    Abstract : The stomach is frequently exposed to hazardous agents and to resist this harsh environment, several protective mechanisms exist. Of special interest is the gastric pathogen Helicobacter pylori which causes gastritis, ulcers and cancer but the mechanism leading to these diseases are still unclear. However it is very likely that H. READ MORE

  2. 2. Gut peptides in gastrointestinal motility and mucosal permeability

    Author : Md. Abdul Halim; Webb Dominic-Luc; Per M Hellström; Lars Fändriks; Uppsala universitet; []
    Keywords : Gut regulatory peptides; Neuropeptides; Gastrointestinal mucosal permeability; Gastrointestinal motility; GLP-1; NPS; ROSE-010;

    Abstract : Gut regulatory peptides, such as neuropeptides and incretins, play important roles in hunger, satiety and gastrointestinal motility, and possibly mucosal permeability. Many peptides secreted by myenteric nerves that regulate motor control are also produced in mucosal epithelial cells. READ MORE

  3. 3. Prevention of Postoperative Duodenal Ileus by COX-2 Inhibition Improves Duodenal Function in Anaesthetised Rats

    Author : John Sedin; Olof Nylander; Markus Sjöblom; Lars Fändriks; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; duodenum; motility; enteric nervous system; luminal alkalinisation; CFTR; VIP; luminal Cl-; fluid secretion; solute absorption; mucosal permeability; 51Cr-EDTA; luminal osmolality; luminal hypertonicity; glucose; mannitol; orange juice; parecoxib; hexamethonium; mecamylamine; Physiology; Fysiologi;

    Abstract : Abdominal surgery inhibits gastrointestinal motility, a phenomenon referred to as postoperative ileus. Since the postoperative ileus disturbs duodenal physiology it is important to minimize the side effects of this condition. READ MORE