Search for dissertations about: "Lars-Owe Koskinen"

Showing result 1 - 5 of 8 swedish dissertations containing the words Lars-Owe Koskinen.

  1. 1. Effects of TRH, naloxone and morphine on cerebral and some other peripheral blood flows : evidence for a physiological role of TRH in cardiovascular control

    Author : Lars-Owe D. Koskinen; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  2. 2. On evolution of intracranial changes after severe traumatic brain injury and its impact on clinical outcome

    Author : Lukas Bobinski; Lars-Owe Koskinen; Magnus Olivecrona; Peter Lindvall; Marklund Niklas; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe traumatic brain injury; ICP targeted therapy; ICP; decompressive craniectomy; S100B; NSE; cranioplasty; neurokirurgi; Neurosurgery;

    Abstract : Severe traumatic brain injury (sTBI) is a cause of death and disability worldwide and requires treatment at specialized neuro-intensive care units (NICU) with a multimodal monitoring approach. The CT scan imaging supports the monitoring and diagnostics. The level of S100B and neuron specific enolase (NSE) reflects the severity of the injury. READ MORE

  3. 3. Pressure autoregulation of cerebral blood flow in traumatic brain injury and aneurysmal subarachnoid hemorrhage

    Author : Ulf Johnson; Per Enblad; Lars-Owe Koskinen; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; autoregulation; traumatic brain injury; subarachnoid hemorrhage; Neurosurgery; Neurokirurgi;

    Abstract : The ability of the brain to keep a stable and adequate cerebral blood flow (CBF) independently of fluctuations in systemic blood pressure is referred to as cerebral pressure autoregulation (CPA). When the brain is injured by trauma or hemorrhage, this ability may be impaired, leaving the brain vulnerable to events of high or low blood pressure. READ MORE

  4. 4. Subarachnoid haemorrhage : clinical and epidemiological studies

    Author : Cecilia Lindgren; Silvana Naredi; Magnus Hultin; Lars-Owe Koskinen; Elisabeth Ronne-Engström; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Subarachnoid haemorrhage; ADMA; Cortisol; EEG; inflammation; epidemiology; endothelium; arginine; anestesiologi; Anaesthesiology; neurokirurgi; Neurosurgery; epidemiologi; Epidemiology;

    Abstract : Background: Subarachnoid haemorrhage (SAH) is a severe stroke that in 85% of all cases is caused by the rupture of a cerebral aneurysm. The median age at onset is 50-55 years and the overall mortality is approximately 45%.Sufficient cortisol levels are important for survival. READ MORE

  5. 5. On severe traumatic brain injury : aspects of an intra cranial pressure-targeted therapy based on the Lund concept

    Author : Magnus Olivecrona; Lars-Owe D Koskinen; Bertil Romner; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; severe traumatic brain injury; ICP targeted therapy; ICP; hemicraniectomy; seizures; prostacyclin; microdialysis; outcome; S100B; NSE; Neurosurgery; Neurokirurgi;

    Abstract : Severe Traumatic Brain Injury (sTBI) is a major cause of mortality and morbidity. At the Department of Neurosurgery Umeå University Hospital subjects with sTBI are treated with an intracranial pressure (ICP) guided therapy based on physiological principles, aiming to optimise the microcirculation of the brain so avoiding secondary brain injuries. READ MORE