Search for dissertations about: "Latent autoimmune diabetes in adults"

Showing result 1 - 5 of 12 swedish dissertations containing the words Latent autoimmune diabetes in adults.

  1. 1. Clinical, Genetic and Metabolic Characterisation of LADA (Latent Autoimmune Diabetes in Adults)

    Author : ÅsaLinda Lethagen; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolic syndrome; insulin sensitivity; insulin secretion; GADabs; glutamic acid decarboxylase autoantibodies; Type 2 diabetes; LADA; Type 1 diabetes; IDDM1; IDDM2; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Latent autoimmune diabetes in adults (LADA) comprises about 10% of patients initially diagnosed with type 2 diabetes but who are positive for pancreatic islet antibodies, especially to glutamic acid decarboxylase (GADabs). The present studies focused on clinical, genetic and metabolic characterisation of patients with LADA. READ MORE

  2. 2. Autoimmune markers in autoimmune diabetes

    Author : Manu Gupta; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HLA; MICA; type 1 diabetes; LADA; Coxsackie virus B; autoantibodies; newborn screening;

    Abstract : Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6 (DQA1*0102-DQB1*0602) is negatively associated with the disease in Caucasians. READ MORE

  3. 3. Diabetes Mellitus at the Time for Diagnosis : Studies on Prognostic Factors

    Author : Mats Martinell; Jan Stålhammar; Johan Hallqvist; Mozhgan Dorkhan; Claes-Göran Östenson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; New-onset Diabetes Mellitus; socioeconomic position; epidemiology; diabetes complications; diabetic retinopathy; cellular immunology; diabetes classification; type 2 diabetes; latent autoimmune diabetes in adults LADA ; type 1 diabetes; Allmänmedicin; Family Medicine; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Abstract : The aim for this thesis was to identify prognostic factors for chronic diabetes complications that exist at the time of diabetes diagnosis.Low level of education (... READ MORE

  4. 4. Genetic interaction between Type 1 and Type 2 diabetes

    Author : Haiyan Li; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; IDDM2.; Insulin gene VNTR; HLA; IDDM1; mixed type 1 2; Mixed type 1 type 2 diabetes families; LADA; GADabs; Autoantibodies against GAD65; Type 1 diabetes; Type 2 diabetes; diabetology; secreting systems; sekretion; diabetologi; Endokrinologi;

    Abstract : There are two major types of diabetes, type 1 and type 2 diabetes. Similarly characterized by hyperglycaemia and long term micro- and macrovascular complications, type 1 and type 2 diabetes have different underlying pathophysiologic processes. In Scandinavia, type 1 diabetes is common; type 2 diabetes accounts for 85% of all cases with diabetes. READ MORE

  5. 5. Genetics of diabetic subtypes

    Author : Camilla Cervin; Diabetes - klinisk obesitasforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; Mutation; Association; Genetics; LADA; Diabetes; MODY; sekretion; diabetologi;

    Abstract : There are two major types of diabetes mellitus, Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D), however a number of subtypes have been defined and classified. Maternally Inherited Diabetes and Deafness (MIDD) and Maturity Onset Diabetes of the Young (MODY) are monogenic forms, whereas Latent Autoimmune Diabetes in Adults (LADA) is thought to be a polygenic subtype similar to T1D. READ MORE