Search for dissertations about: "Laura C. Bott"

Found 1 swedish dissertation containing the words Laura C. Bott.

2. 1. Spinal and bulbar muscular atrophy : new insights into the disease mechanism and prospects for pharmacological therapy

   Author : Laura C Bott; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Expansion of a polyglutamine-encoding trinucleotide CAG repeat in the androgen receptor (AR) gene causes spinal and bulbar muscular atrophy (SBMA, or Kennedy’s disease). SBMA is an adult-onset disease characterized by progressive muscle weakness and atrophy due to the degeneration of lower motor neurons in the brainstem and spinal cord. READ MORE