Search for dissertations about: "Lena Mäler"

Showing result 1 - 5 of 22 swedish dissertations containing the words Lena Mäler.

  2. 1. NMR relaxation studies of molecular dynamics and nuclear spin interactions in solution

    Author : Lena Mäler; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molekylbindning; Elektronspinmätning;

    Abstract : .... READ MORE

  4. 2. Improved Methods for Characterization of Protein Dynamics by NMR spectroscopy and Studies of the EphB2 Kinase Domain

    Author : Alexandra Ahlner; Patrik Lundström; Bengt-Harald Jonsson; Lena Mäler; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Proteins are essential for all known forms of life and in many lethal diseases protein failure is the cause of the disease. To understand proteins and the processes they are involved in, it is valuable to know their structures as well as their dynamics and interactions. READ MORE

  5. 3. The Application of isotropic bicelles as model membranes

    Author : August Andersson; Lena Mäler; G Arthur III Palmer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bicelle; membrane; peptide; spectroscopy; NMR; Molecular biophysics; Molekylär biofysik;

    Abstract : Isotropic bicelles are disc-shaped aggregates of lipids and detergents, and are suitable model systems for high-resolution NMR studies of membrane-interacting peptides. In this thesis the structures for the two peptides motilin and transportan were determined by homonuclear 1H methods in the presence of bicelles, and the structure of the bovine prion protein peptide (bPrPp) was solved in the presence of DHPC micelles. READ MORE

  6. 4. Protein Structure and Interaction in Health and Disease

    Author : Cecilia Andrésen; Maria Sunnerhagen; Patrik Lundström; Lena Mäler; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : This thesis focuses on protein structure, dynamics and interaction and their relation to human disease. In particular, the biophysical and structural properties of both well-ordered and partially disordered proteins are studied using a range of biophysical techniques such as circular dichroism spectroscopy, fluorescence spectroscopy, mass spectrometry and nuclear magnetic resonance spectroscopy. READ MORE

  7. 5. Structure and Dynamics of Membrane Associated Peptides

    Author : Henrik Biverståhl; Lena Mäler; Charles R. Sanders; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biophysics; Biofysik; Biophysics; biofysik;

    Abstract : The peptide-membrane interaction is a key element for many biological functions, from cell signaling to cell internalization. In this thesis the peptide-membrane interaction of six different peptides have been studied with respect to their structure, membrane location and dynamics with spectroscopic methods. READ MORE