Search for dissertations about: "Leonard"

Showing result 1 - 5 of 31 swedish dissertations containing the word Leonard.

  2. 1. Cellular Lignin Distribution Patterns and their Physiological Relevance

    Author : Leonard Blaschek; Edouard Pesquet; András Gorzsás; Annelie Carlsbecker; Ulla Westermark; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The diverse morphological shapes of plants are made possible by the structural rigidity provided by cell walls. In order to support vertical growth and long distance water transport, cell walls need to resist a variety of biological and physical stresses. READ MORE

  4. 2. The evaluation, preoperative and operative aspects of abdominal wall reconstruction for giant ventral hernia

    Author : Leonard Clay; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : BACKGROUND: The optimal method for surgical repair of giant ventral hernia remains to be determined. Different concepts for reinforcement have been used, which have decreased the risk for recurrence. READ MORE

  5. 3. Growth factor pathways in human cancer : functional and therapeutic implications

    Author : Leonard Girnita; Karolinska Institutet; Karolinska Institutet; []
    Keywords : IGF-1R; growth factors; p53; fusion protein; tyrosine kinase inhibitors; ubiquitin;

    Abstract : The multi-step development of tumors involves numerous changes at genomic level such as oncogene activation, loss of function of tumor suppressor genes and translocations resulting in fusion genes that encodes for chimeric proteins with tumorigenic functions etc. However, in the selection leading to cancer in somatic tissues it is likely that the cancer cells make use of the normal extracellular signaling for proliferation and/or anti-apoptosis to create growth advantage over the normal cells. READ MORE

  6. 4. Studies on genetic and epigenetic regulation of gene expression dynamics

    Author : Leonard Hartmanis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The information required to build an organism is contained in its genome and the first biochemical process that activates the genetic information stored in DNA is transcription. Cell type specific gene expression shapes cellular functional diversity and dysregulation of transcription is a central tenet of human disease. READ MORE

  7. 5. Functional aspects of cellobiose dehydrogenase Applications for biosensor development

    Author : Leonard Stoica; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elektrokemi; Electrochemistry; Analytisk kemi; Analytical chemistry; bioelectrochemistry; direct electron transfer; lactose biosensor;

    Abstract : Electrochemcial investigations were conducted for elucidating and understanding the relation between the various electron transfer processes occurring in cellobiose dehydrogenase (CDH) bound to an electrode surface. Substrate inhibition caused by cellobiose was proven to act in competition with the electron transfer to a two-electron acceptor and under a partial inhibition mechanism for the internal electron transfer process. READ MORE