Search for dissertations about: "Leonardo Vargas-Vallejo"

Found 1 swedish dissertation containing the words Leonardo Vargas-Vallejo.

2. 1. Subcellular localization and signalling of Brutons tyrosine kinase (Btk)

   Author : Leonardo Vargas-Vallejo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : B-cells; Brutons tyrosine kinase; X-linked agammaglobulinemia; pleckstrin homology domain; cytoskeleton; nucleocytoplasmic shuttling; caveolin-1; ubiquitin; SUMO-1.;

   Abstract : Brutons tyrosine kinase (Btk) is a non-receptor tyrosine kinase related to the Src family of kinases. Mutations in various parts of the gene have been shown to cause X-linked agammaglobulinemia (XLA), a primary immunodeficiency in humans, characterized by a defect in B-cell development. READ MORE