Search for dissertations about: "Leopold L. Ilag"

Showing result 1 - 5 of 6 swedish dissertations containing the words Leopold L. Ilag.

  2. 1. Mass Spectrometry of Biologically Active Small Molecules : Focusing on polyphenols, alkaloids and amino acids

    Author : Zdeněk Spáčil; Leopold L. Ilag; Frantisek Turecek; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LC-MS; LDI; Mass spectrometry; HPLC; UHPLC; polyphenols; phenolic acids; BMAA; Separation methods; Separationsmetoder; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. READ MORE

  4. 2. Strategies to explore the membrane proteome of a cell

    Author : Gianluca Maddalo; Leopold L. Ilag; Peter James; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Proteomics; Escherichia coli; Enterococcus faecalis; Synechocystis; Mass Spectrometry; BN SDS-PAGE; FT-ICR-MS; Myelin P2 protein; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The cell envelope plays key roles in numerous processes such as maintaining cellular integrity, communication with other cells, signal transduction, maintenance of cellular homeostasis, and regulation of the traffic of molecules between the cell and the extracellular milieu. Essential membrane components in many of these processes are proteins. READ MORE

  5. 3. Capturing transient peptide assemblies associated with Alzheimer's disease : Native mass spectrometry studies of amyloid-β oligomerization

    Author : Nicklas Österlund; Astrid Gräslund; Leopold L. Ilag; Mikael Oliveberg; Sheena E. Radford; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein aggregation; amyloid-β; neurodegeneration; Alzheimer’s disease; chaperones; DnaJ; biomembranes; native mass spectrometry; Biophysics; biofysik;

    Abstract : Correct folding of proteins is essential for maintaining a functional living cell. Misfolding and aggregation of proteins, where non-native intermolecular interactions form large and highly ordered amyloid aggregates with low free energy, is hence associated with multiple diseases. READ MORE

  6. 4. Mass Spectrometry of Non-protein Amino Acids : BMAA and Neurodegenerative Diseases

    Author : Liying Jiang; Leopold Ilag; Jonas Bergquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurodegenerative diseases; BMAA; Isomers; LC-MS MS; Cyanobacteria; Diatoms; Seafood contamination; Analytical Chemistry; analytisk kemi;

    Abstract : Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. READ MORE

  7. 5. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods

    Author : Javier Zurita; Leopold Ilag; Ulrika Nilsson; Margareta Törnqvist; Natalia Tretyakova; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; amino acids; LC MS; fixed-charge derivatization; BMAA; chiral separation; pheromones; arctic aerosols; serum albumin adducts; benzo[a]pyrene diol epoxides; high-resolution MS; Analytical Chemistry; analytisk kemi;

    Abstract : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). READ MORE