Search for dissertations about: "Leucovorin"

Found 4 swedish dissertations containing the word Leucovorin.

  1. 1. Folates in the treatment of colorectal cancer

    Author : Helena Taflin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; Colorectal cancer; leucovorin; modufolin; LC-MS MS; polymorphisms; MTHFR; adjuvant chemotherapy;

    Abstract : ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most common cancers in the world, and radical surgery with total removal of the tumour (RO-resection) is the single most important treatment. However, chemotherapy is recommended for patients with risk factors and patients with metastatic disease. READ MORE

  2. 2. Chemical transformation of the anticancer drug oxaliplatin

    Author : Elin Jerremalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxaliplatin is a new platinum based cytostatic drug. It is used in combination with 5- fluorouracil and leucovorin, both as palliative and adjuvant treatment of metastatic colorectal cancer. Various biotransformation products are formed non-enzymatically after oxaliplatin administration. READ MORE

  3. 3. Biotransformation of the antineoplastic drug oxaliplatin : importance for effects and side effects

    Author : Elin Jerremalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxaliplatin is a platinum-based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin for palliative and adjuvant treatment of metastatic colorectal cancer. READ MORE

  4. 4. Intraperitoneal 5-Fluorouracil treatment of cancer - clinical and experimental studies

    Author : Mikael Öman; Peter Naredi; Larsolof Hafström; Johan Permert; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; intraperitoneal; 5-fluorouracil; pancreas cancer; vasopressin; Xenon-clearance; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Background:Pancreas cancer is a most aggressive malignancy. More than 80% of patients diagnosed with pancreas cancer, exhibit such advanced disease, that curative surgery is impossible. Systemic chemotherapy prolongs survival to 5-9 months. READ MORE