Search for dissertations about: "Leukocyte activation"
Showing result 16 - 20 of 120 swedish dissertations containing the words Leukocyte activation.
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16. Platelet and leukocyte activation and their interaction : in experimental prothrombotic and inflammatory states
Abstract : Atherosclerotic disease is associated with inflammation and thrombosis, both of which involve multi-cellular activation and interaction. The present work has investigated the mechanisms of platelet leukocyte cross-talk in vitro, and explored the possibility of multi-cellular activation in vivo in prothrombotic and inflammatory models in healthy volunteers. READ MORE
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17. Signaling and Adhesive Mechanisms in Acute Pancreatitis
Abstract : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. READ MORE
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18. Effects of high glucose on platelet activation
Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated the mechanisms underlying hyperglycaemia-induced platelet hyperreactivity and its impact in diabetic patients. READ MORE
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19. Leukocyte receptor alternations during systemic inflammatory responses
Abstract : The leukocyte adhesion molecule CD llb is very important when granulocytes and monocytes leave the blood stream. This adhesion molecule is stored preformed intracellularly, and can upon stimulation of the cells by, for example, complement split products, be mobilized to the cell surface. READ MORE
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20. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function
Abstract : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. READ MORE