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Showing result 1 - 5 of 32 swedish dissertations matching the above criteria.

  2. 1. Helicobacter pylori adhesion and patho-adaptation : the role of BabA and SabA adhesins in persistent infection and chronic inflammation

    Author : Jafar Mahdavi; Henrik Clausen; Umeå universitet; []
    Keywords : H. pylori; BabA; adhesin; Lewis b; MUC5AC; sialyl-dimeric-Lewis x; chronic inflammation; SabA; Lewis x; LPS; odontologi; Odontology;

    Abstract : Helicobacter pylori (H. pylori) is a human-specific gastric pathogen which is responsible for a spectrum of diseases ranging from superficial gastritis to gastric and duodenal ulceration, and which is also highly associated with gastric cancer. The pathogenesis of severe gastric disorders caused by H. READ MORE

  4. 2. Evaluation of fucosylated receptors for Cholera toxin in the human small intestine

    Author : Jakob Cervin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera toxin; Lewis antigen; HBGA; HMO; Fucose; GM1;

    Abstract : Cholera toxin (CT) produced by Vibrio cholerae is the causative agent for the diarrheal disease cholera. Cholera is yearly afflicting millions and is estimated to kill over 100 000 people every year. In this thesis I aimed to better understand the role of noncanonical CT receptors, e.g. READ MORE

  5. 3. Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation

    Author : Sara Lindén; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; host-parasite interactions; H. pylori adhesin; mucin; Lewis antigen;

    Abstract : Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. READ MORE

  6. 4. Synthesis of oligosaccharides of the Lewis blood group antigen family

    Author : Linnéa Skantz; Stockholms universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  7. 5. Synthesis of biologically active oligosaccharides of the Lewis b family and investigations towards the synthesis of glycoclusters

    Author : Linnéa Skantz; Martina Lahmann; Thisbe Lindhorst; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Lewis b; lactosamine; dendrimers; oxazolidinone; Organic synthesis; Organisk syntes; organisk kemi; Organic Chemistry;

    Abstract : The gastric pathogen Helicobacter pylori is a Gram negative bacterium which may cause diseases such as peptic ulceration and gastric adenocarcinoma. It colonises a host by attaching to the gastric epithelial cells, an attachment mediated by outer membrane proteins on the bacterial surface, e.g, the blood group antigen binding adhesin, BabA. READ MORE