Search for dissertations about: "Lewis antigens"

Showing result 16 - 20 of 28 swedish dissertations containing the words Lewis antigens.

  2. 16. Genome-plasticity and adaption in Helicobacter pylori

    Author : Christina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Helicobacter pylori is a gastric bacterial pathogen that infects an estimated half. of the human population. The infection is primarily acquired during early childhood and causes a persistent infection that is usually not eradicated by the host immune system. Although most infected individuals. READ MORE

  4. 17. Modulation of experimental T cell autoimmunity in the nervous system with emphasis on nasal tolerance

    Author : Xue-Feng Bai; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Experimental autoimmune neuritis (EAN) and encephalomyelitis (EAE) are animal models of Guillian-Barre syndrome (GBS) and multiple sclerosis (MS), representing human demyelinating diseases of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. CD4+ T cells recognizing myelin antigens and producing cytokines play central roles in the pathogenesis of both EAN and EAE and perhaps of GBS and MS. READ MORE

  5. 18. Genetic adaptations of Helicobacter pylori during gastric disease progression

    Author : Helene Kling Bäckhed; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Helicobacter pylori colonizes the stomachs of approximately half of all humans. In the absence of treatment, H. pylori can persist throughout the life of the host. Although most infected individuals are asymptomatic, a significant proportion develops peptic ulcer disease, chronic atrophic gastritis (ChAG) or gastric adenocarcinoma. READ MORE

  6. 19. Host susceptibility to rotavirus infection and development of antibody-based immunotherapy

    Author : Gökçe Günaydın; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rotavirus infects mature enterocytes of the small intestine of young children and cause gastroenteritis, leading to approximately 500 000 deaths annually worldwide, 85 % of which occur in the developing world. The main objectives of the thesis were to investigate host genetic factors leading to differential susceptibility to rotavirus infections and to develop an antibody-based oral therapy against the infections. READ MORE

  7. 20. Helicobacter pylori : molecular mechanisms for variable adherence properties

    Author : Anna Vallström; Anna Arnqvist; Kristian Riesbeck; Umeå universitet; []
    Keywords : H. pylori; adherence; BabA; SabA; Leb; sLex; phase variation; recombination; vesicles;

    Abstract : More than half of all people worldwide are infected with H. pylori. The infection always cause a gastric inflammation that may develop into peptic ulcer disease or gastric cancer. Attachment proteins, adhesins, mediate specific adherence of H. READ MORE