Search for dissertations about: "Lewis antigens"

Showing result 6 - 10 of 28 swedish dissertations containing the words Lewis antigens.

  2. 6. Evaluation of fucosylated receptors for Cholera toxin in the human small intestine

    Author : Jakob Cervin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera toxin; Lewis antigen; HBGA; HMO; Fucose; GM1;

    Abstract : Cholera toxin (CT) produced by Vibrio cholerae is the causative agent for the diarrheal disease cholera. Cholera is yearly afflicting millions and is estimated to kill over 100 000 people every year. In this thesis I aimed to better understand the role of noncanonical CT receptors, e.g. READ MORE

  4. 7. Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation

    Author : Sara Lindén; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; host-parasite interactions; H. pylori adhesin; mucin; Lewis antigen;

    Abstract : Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. READ MORE

  5. 8. Adaptation of Helicobacter pylori Adherence Properties in Promotion of Host Tropism and Inflammatory Disease

    Author : Marina Aspholm; Rino Rappuoli; Umeå universitet; []
    Keywords : H. pylori; BabA; SabA; adhesin; blood group antigens; sialylated; phase variation; hemagglutination; selectin; adaptation; odontologi; Odontology;

    Abstract : Being among the most prevalent of persistent infectious agents in humans worldwide, Helicobacter pylori induces chronic inflammation (gastritis), which may progress to peptic ulceration and stomach cancer. The ability to adhere to the gastric mucosa is considered to be both a colonization and virulence property of H. pylori. For adherence, H. READ MORE

  6. 9. Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses

    Author : Tanvir Ahmed; Göteborgs universitet; []
    Keywords : Vibrio cholerae; ETEC; oral vaccine; CS6; CFA I; Lewis blood group; zinc; breast feeding; T cell; B cell;

    Abstract : Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses Abstract Vibrio cholerae O1 and enterotoxigenic Escherichia coli (ETEC) together account for the majority of bacterial causes of acute dehydrating diarrhea in children in Bangladesh. Vaccines should be considered as an important public health tool for prevention of these diarrheal diseases. READ MORE

  7. 10. Gastrointestinal norovirus infections and the development of the next generation of mucosal vaccines

    Author : Inga Rimkute; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human norovirus; gastrointestinal infection; mucosal vaccine; subcomponent vaccine; human intestinal enteroids; histo-blood group antigens; lipidomics; glycoproteomics; glycosphingolipids;

    Abstract : Human norovirus (HuNoV) is the causative agent of the winter vomiting disease and the leading cause of outbreaks of gastrointestinal infections across all settings and age groups in the world. The virus is highly contagious making outbreaks difficult or often impossible to control and having a high impact on societal costs and resources. READ MORE