Search for dissertations about: "Lin-Sheng Xiao"

Found 1 swedish dissertation containing the words Lin-Sheng Xiao.

2. 1. Studies on the mechanism for natural killer cell cytotoxicity and its regulation

   Author : Lin-Sheng Xiao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : natural killer cell; nitric oxide; cytotoxicity; nitric oxide synthase; cyclic GMP; cyclic AMP; immunol regulation;

   Abstract : Since the proposed perforin-granzymes exocytosis can not sufficiently account for NK cell mediated cytolysis, the existence of a new and yet unknown mechanism for induction of the damage to targets by NK cells has been suggested. Our data illustrates that NK cell oncolytic activity has a requirement for L-arginine. READ MORE