Search for dissertations about: "Linda Rosengren"

Found 3 swedish dissertations containing the words Linda Rosengren.

2. 1. Identification and evaluation of growth hormone antagonists

   Author : Linda Rosengren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : States in which Growth hormone (GH) levels are elevated have been implicated in several physiological disorders such as acromegaly, diabetic complications and progression of malignancies. Classical treatments for acromegaly are surgery and radiotherapy but also pharmacological therapies exist. READ MORE

4. 2. Targeting the GH/IGF-1 axis with novel, small molecule inhibitors

   Author : Linda Rosengren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The growth hormone (GH) / insulin-like growth factor (IGF) family of ligands, binding proteins and receptors play multiple roles in cell growth, metabolism and development. In addition, numerous studies have demonstrated the pathophysiological importance of the GH/IGF-1 axis. READ MORE

5. 3. Structure and function of relaxins

   Author : Linda M. Haugaard-Kedström; Johan Rosengren; Torleif Härd; Linnéuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; relaxin; insulin-like peptide; peptide hormone; peptide synthesis and NMR; Organic Chemistry; Organisk kemi;

   Abstract : The relaxin/insulin superfamily is a group of peptide hormones that consists of ten members in human, namely relaxins 1-3, insulin-like peptides (INSL) 3-6, insulin and insulin-like growth factors (IGF) I-II. These peptides have various functions in the body, such as regulating growth, blood glucose levels,  collagen metabolism, germ cell maturation and appetite. READ MORE