Search for dissertations about: "Lipase"
Showing result 21 - 25 of 225 swedish dissertations containing the word Lipase.
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21. Synthetic Transformations via Metal- and Enzyme-Catalyzed Dynamic Kinetic Resolution
Abstract : This thesis deals with the preparation of a new half-sandwich type ruthenium(II)- catalyst for racemization of optically active secondary alcohols and the development of a highly efficient method in combination with lipases such as Candida antarctica lipase B and Pseudomonas cepacia lipase for dynamic kinetic resolution of various functionalized alcohols under mild reaction conditions.It was shown that the RuCl(CO)2(η5-C5Ph5) complex can racemize optically active aliphatic and aromatic secondary alcohols at room temperature in rather short times. READ MORE
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22. Enthalpy and Entropy in Enzyme Catalysis : A Study of Lipase Enantioselectivity
Abstract : Biocatalysis has become a popular technique in organic synthesis due to high activity and selectivity of enzyme catalyzed reactions. Enantioselectivity is a particularly attractive enzyme property, which is utilized for the production of enantiopure substances. READ MORE
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23. Lipase Specificity and Selectivity : Engineering, Kinetics and Applied Catalysis
Abstract : The specificity and selectivity of the enzyme Candida antarctica lipase B (CALB) were studiedfor several substrates and applications.With help of molecular modeling, the active site of CALB was redesigned for the ring openingpolymerization of D,D‐lactide. READ MORE
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24. Carboxylic ester hydrolase in acute pancreatitis : a clinical and experimental study
Abstract : Diagnosis of acute pancreatitis (AP) is erroneous in up to one third of patients when based on clinical criteria and elevated serum amylase values. Furthermore, according to autopsy reports fatal pancreatitis remains clinically undiagnosed in 22 to 86 % of hospitalised patients. READ MORE
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25. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity
Abstract : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. READ MORE