Search for dissertations about: "Liu X cancer"

Showing result 1 - 5 of 29 swedish dissertations containing the words Liu X cancer.

  2. 1. Somatostatin effects on the proteome of human prostate cancer cells

    Author : Zhaoxu Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The transition of prostate cancer from androgen dependent to the therapy resistant androgen independent state, is a large and persistent problem in the clinical management of prostate cancer. The aim of this thesis was to study somatostatin effects on the proteome of prostate cancer cells, to identify differences in protein expression in androgen dependent and androgen independent prostate cancer cells, and to explore possibilities to enhance the somatostatin receptor expression through pre-treatment with sms, 5-aza and TSA (DNA methylation/HDAC inhibitors). READ MORE

  4. 2. The role of the androgen receptor and hydroxysteroid 17β dehydrogenase in breast cancer : Impact on tamoxifen treatment

    Author : Erik Hilborn; Agneta Jansson; Olle Stål; Yvonne Ceder; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The healthy breast is a tissue composed of centrally located milk producing glands connected to the nipple by ducts, surrounded by fat tissue and connective tissue. The growth of the breast is primarily mediated by the estrogens, while the androgens mediate tissue homeostasis and protect against growth signals. READ MORE

  5. 3. Deep Learning for Digital Pathology in Limited Data Scenarios

    Author : Karin Stacke; Jonas Unger; Gabriel Eilertsen; Claes Lundström; Henning Müller; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical imaging; Digital pathology; Radiology; Machine learning; Deep learning.;

    Abstract : The impressive technical advances seen for machine learning algorithms in combination with the digitalization of medical images in the radiology and pathology departments show great promise in introducing powerful image analysis tools for image diagnostics. In particular, deep learning, a subfield within machine learning, has shown great success, advancing fields such as image classification and detection. READ MORE

  6. 4. Biomarkers In Brain Tumors With Focus On Glioblastoma

    Author : Malgorzata Lysiak; Peter Söderkvist; Annika Malmström; Olle Stål; Mattias Belting; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; MGMT; Biomarker; Sex differences; Androgen receptor; Loss of chromosome Y;

    Abstract : The primary brain tumors, gliomas, are not very common but they are deadly. Each year in Sweden around 500 patients will be diagnosed with a glioma and unfortunately most of them will have the most aggressive type, glioblastoma (GBM). Median survival, even if treated, is poor (14-17 months). READ MORE

  7. 5. Understanding Skin Cancer Risk and Prevention : with Emphasis on Actinic Keratosis Patients

    Author : Ghassan Guorgis; Magnus Falk; Chris Anderson; Magdalena Claeson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The rising incidence of skin cancer globally makes it important to emphasize preventive measures that promote sun protection, particularly among individuals with phenotypic predisposition and/or risky sun habits. Actinic keratosis (AK) is the predominant actinic lesion observed in fair-skinned populations, recognized as a sign of actinic skin damage and as an occasional precursor to squamous cell carcinoma (SCC). READ MORE