Search for dissertations about: "Liver disease prediction"

Showing result 1 - 5 of 14 swedish dissertations containing the words Liver disease prediction.

  1. 1. Proteomics-informed analysis of drug disposition in the human liver and small intestine

    Author : Christine Wegler; Per Artursson; Pär Matsson; Tommy B Andersson; Manthena Varma; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; protein concentration; drug disposition; drug transport; drug metabolism; human small intestine; human liver; human hepatocytes; human liver microsomes; inter-individual variability; drug clearance; obesity; prediction model; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Orally administered drugs are absorbed in the intestine and generally metabolized in the liver. Therefore, understanding factors determining drug distribution and elimination in these tissues is important. READ MORE

  2. 2. Pancreatic Neuroendocrine Tumors : Surgical Treatment and Follow-up

    Author : Josefine Kjaer; Olov Norlén; Kjetil Soreide; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic neuroendocrine tumor; surgery; liver metastases; hepatic resection; liver transplantation; recurrence; Kirurgi; Surgery;

    Abstract : Pancreatic neuroendocrine tumors (Pan-NET), are rare, heterogenous and derive from the hormone producing cells in the pancreas. The functioning tumors that overproduce hormones cause clinical syndromes with specific symptoms due to the hormonal production. READ MORE

  3. 3. Risk Factors and Predictors of Heart Failure: from Incidence to Prognosis

    Author : Constantinos Ergatoudes; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : heart failure; prognosis; characteristics; risk factors; incidence; prediction;

    Abstract : Background: Heart failure (HF) is a major public health problem affecting at least 26 million people worldwide and one of the leading causes of disability and death. Aims: To identify characteristics associated with improved or worsened prognosis in patients with established HF and to study factors associated with higher risk for the incidence of HF in the general population. READ MORE

  4. 4. Enhancing prediction and causal inference in metabolic dyshomeostasis

    Author : Naeimeh Atabaki Pasdar; Genetisk och molekylär epidemiologi; []

    Abstract : This thesis is focused on two globally prevalent diseases: i) non-alcoholic fatty liver disease (NAFLD) and ii) type 2 diabetes (T2D), with an overall aim of improving prediction and causal inference in the context of these conditions. Our projects were mainly conducted using IMI DIRECT and UK Biobank datasets including multi-omics data, extensive environmental exposures, and biological intermediates. READ MORE

  5. 5. Quantitative evaluation of liver function using gadoxetic acid-enhanced MRI

    Author : Qiang Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Before liver resection, a reliable and accurate assessment of the liver function is essential to ensure a safe surgery and avoid unfavorable complications such as post-hepatectomy liver failure (PHLF). Gadoxetic acid enhanced magnetic resonance imaging (MRI) is a routinely used imaging modality for tumor detection and characterization. READ MORE