Search for dissertations about: "Liver pathology"

Showing result 1 - 5 of 41 swedish dissertations containing the words Liver pathology.

  2. 1. Two Types of Fibrils in ATTR Amyloidosis : Implications for Clinical Phenotype and Treatment Outcome

    Author : Elisabet Ihse; Per Westermark; Per Hammarström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; transthyretin; familial amyloidotic polyneuropathy; TTRV30M; non-TTRV30M; wild-type; liver transplantation; cardiomyopathy; fibril composition; Biokemi; Biochemistry; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Experimentell patologi; Experimental Pathology; Medical Biochemistry; Medicinsk biokemi; Molecular Biology; Molekylärbiologi; Pathology; Patologi;

    Abstract : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. READ MORE

  4. 2. On CXC Chemokines in Endotoxin-Induced Liver Injury

    Author : Xiang Li; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; orthopaedics; traumatology; Kirurgi; Surgery; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; intravital microscopy; liver damage; Adhesion; CXC chemokines;

    Abstract : Leukocyte recruitment is a rate-limiting step in endotoxemic liver injury. Leukocyte extravasation is a multistep process, supported by multiple combinations of adhesion molecules and chemokine receptors. This thesis examined the mechanisms of activation, adhesion and extravascular infiltration of leukocytes in endotoxin-induced liver injury. READ MORE

  5. 3. Cellular and molecular mechanisms in immune mediated hepatic fibrosis. A study of the inflammatory syndrome and fibrosis development of the NIF mouse liver

    Author : Julia Nilsson; Autoimmunitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibrosis; liver; mouse model; NKT cells; type 2 inflammation; inflammasome;

    Abstract : Fibrosis is the result of dysregulated inflammation and tissue repair, and is characterized by the excessive accumulation of extra cellular matrix (ECM) proteins. It causes detrimental effects to the afflicted tissue and can subsequently lead to organ failure. READ MORE

  6. 4. Renal injury in liver transplantation clinical and mechanistic studies

    Author : Åsa Norén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver transplantation; Renal injury; Ischemia reperfusion injury;

    Abstract : ABSTRACT Background: Renal injury in liver transplantation (LT) is common and presents both as early and late insufficiency. These conditions are interconnected and have substantial impact on the long-term outcome. READ MORE

  7. 5. Associated disorders in celiac disease

    Author : Peter Elfström; Jonas F. Ludvigsson; Anders Ekbom; Peter Green; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addison; autoimmune; biopsy; celiac; child; cohort study; cancer; heart; liver; lymphoma; thyroid; Paediatric medicine; Pediatrisk medicin; MEDICINE; MEDICIN; Pediatrik; Pediatrics; Epidemiology; Epidemiologi; Medicin; Medicine;

    Abstract : Background: Celiac disease (CD) is an autoimmune disorder that affects genetically susceptible individuals and is induced by dietary gluten. Treatment consists of a lifelong gluten-free diet. CD is common and affects about 1% of the general population. READ MORE