Search for dissertations about: "Ljungan virus"

Showing result 1 - 5 of 6 swedish dissertations containing the words Ljungan virus.

  2. 1. Ljungan Virus Replication in Cell Culture

    Author : Jens-Ola Ekström; Kjell Edman; Glyn Stanway; Högskolan i Kalmar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ljungan virus; picornavirus; parechovirus; 5 - RACE; 5 -end; infectious cDNA clone; real time PCR; virus purification; virion stability; disinfection; aphthovirus-like 2A; Virology; Virologi; Mikrobiologi; Microbiology;

    Abstract : Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also in the United States. LV infected small rodents may suffer from diabetes type 1 and type 2 like symptoms, myocarditis and encephalitis. READ MORE

  4. 2. Apolipoprotein CIII and Ljungan virus in diabetes

    Author : Rebecka Holmberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : It has been shown that there are patients with type 1 diabetes (T1D), whose sera induce an increased activity of voltage-gated Ca2+-channels in pancreatic beta-cells, resulting in increased cytoplasmic free Ca2+ concentration ([Ca2+]i) and apoptosis. Purification of the protein in the active fraction of T1D sera revealed that the observed effects were mediated by apolipoprotein CIII (apoCIII), and this protein was shown to be increased in serum from T1D patients. READ MORE

  5. 3. Genomic Organization and Capsid Architecture of Ljungan Virus : a Novel Member of the Picornaviridae

    Author : Susanne Johansson; Michael Lindberg; Einar Everitt; Tapani Hovi; Högskolan i Kalmar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Virologi; Virologi; Virology;

    Abstract : Ljungan virus är ett virus som isolerades i Sverige i mitten på nittiotalet. Under perioden 1989-1992 avled flera svenska elitorienterare plötsligt i hjärtmuskelinflammation. Man misstänkte att orienterarna kunde ha utsatts för en vektorburen infektion eftersom de exponeras för djur som finns i skog och mark under träning och tävling. READ MORE

  6. 4. Ljungan virus : a novel pathogen : effects on the pregnant female and her offspring

    Author : Annika Samsioe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ljungan virus; IUFD; zoonotic; mouse model; stress; diabetes;

    Abstract : Ljungan virus (LV) was isolated in the mid 1990s from a native rodent, the bank vole (Myodes glareolus), trapped in the Ljungan valley of central Sweden. It is a member of the parecho virus genus in the picorna virus family. READ MORE

  7. 5. Markers of Infection in Childhood Autoimmune Diabetes and Related Disorders

    Author : Anna-Lena Nilsson; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmune type 1 diabetes Ljungan virus antibodies Islet autoantibodies HLA;

    Abstract : The main aim of this thesis was to contribute to the knowledge about mechanisms involved in the development of type 1 diabetes (T1D) and other autoimmune diseases in children. Immune markers in relation to genetic propensity in children with autoimmune disease, mainly T1D and a small group of juvenile idiopathic arthritis (JIA) and thyroiditis (THYR), as well as healthy controls have been studied. READ MORE