Search for dissertations about: "Locus"
Showing result 1 - 5 of 612 swedish dissertations containing the word Locus.
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1. Dopamine neurons in ventral mesencephalon : interactions with glia and locus coeruleus
Abstract : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. READ MORE
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2. Teratogenicity and in vitro fetal thymus toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin and its congeners : segregation with the Ah-locus
Abstract : .... READ MORE
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3. The Carboxyl Ester Lipase Gene. Organization, Evolution and Transcriptional Regulation in Exocrine Pancreas and Mammary Gland
Abstract : The carboxyl ester lipase (CEL) is an important enzyme for the intestinal absorption of dietary lipids. In humans the gene is highly expressed in exocrine pancreas and in the lactating mammary gland. It is secreted in an inactive form and becomes activated by bile salts in the intestine. READ MORE
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4. Genetic Studies of Rheumatoid Arthritis using Animal Models
Abstract : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. READ MORE
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5. Sculpted through Time : Evolution and Function of Serine Proteases from the Mast Cell Chymase Locus
Abstract : Immune cells like NK cells, T cells, neutrophils and mast cells store high amounts of granule serine proteases, graspases. Graspases are encoded from the mast cell chymase locus. The human locus holds four genes: α-chymase, cathepsin G, and granzymes H and B. In contrast, the mouse locus contains at least 14 genes. READ MORE