Search for dissertations about: "Lora Deuitch Weidner"

Found 1 swedish dissertation containing the words Lora Deuitch Weidner.

2. 1. The role of ABC transporters and inflammation in drug-resistant epilepsy

   Author : Lora Deuitch Weidner; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : This thesis explores two pathologies thought to be related to drug resistance in epilepsy that may themselves be causally related: 1) overexpression of drug transporters in capillaries and 2) inflammation. With regard to the first hypothesis, overexpression of the ATP-binding cassette (ABC) transporters, P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), at the blood-brain barrier are thought to contribute to drug resistance in epilepsy. READ MORE