Search for dissertations about: "Loukas Tatidis"

Found 1 swedish dissertation containing the words Loukas Tatidis.

2. 1. Cholesterol turnover in acute myelogenous leukemia with special emphasis on regulation of low density lipoprotein receptor expression in leukemic cells

   Author : Loukas Tatidis; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cellular cholesterol requirements are met by receptor mediated uptake of cholesterol in low density lipoprotein (LDL) particles and/or by endogenous synthesis, the rate limiting enzyme in the synthesis pathway being 3-hydroxy-3-methylglutary coenzyme A (HMG-CoA) reductase. Expressions of both the LDL receptor and HMG-CoA reductase genes are normally under end product repression by cellular cholesterol. READ MORE