Search for dissertations about: "Lrmp"

Found 2 swedish dissertations containing the word Lrmp.

2. 1. Molecular and cellular mechanisms contributing to the pathogenesis of autoimmune diabetes

   Author : Nádia Duarte; Dan Holmberg; David Serreze; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; type 1 diabetes; NOD mouse; susceptibility loci; Idd6; Lrmp; gene; NKT; CD1d; TCR; mast cells; Immunologi; Immunology; Immunologi; medicinsk genetik; Medical Genetics;

   Abstract : Type 1 diabetes is an autoimmune disorder determined both by genetic and environmental factors. The Non-obese diabetic (NOD) mouse is one of the best animal models of this disease. It spontaneously develops diabetes through a process resembling the human pathogenesis. READ MORE

4. 2. Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse

   Author : Marie Lundholm; Dan Holmberg; Vivianne Malmström; Umeå universitet; []
   Keywords : Type 1 Diabetes; NOD mouse; CTLA-4; Ctex; CD3ζ; apoptosis; Idd6; Lrmp; medicinsk genetik; Medical Genetics;

   Abstract : Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and environmental factors. The non-obese diabetic (NOD) mouse is one of the best and most commonly studied animal models for T1D. This mouse strain spontaneously develops diabetes through a process that closely resembles the human pathogenesis. READ MORE