Search for dissertations about: "Lund Patologi"

Showing result 1 - 5 of 21 swedish dissertations containing the words Lund Patologi.

  2. 1. Acute pancreatitis - Cellular response and dynamic inflammatory changes

    Author : Marwan Dib; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Veterinary medicine:surgery; inflammatory mediators.; adhesion molecules; endothelial barrier dysfunction; inflammatory response; mast cell; abdominal sepsis; Acute pancreatitis; physiology; pathology; clinical studies; Veterinärmedicin:kirurgi; fysiologi; patologi; kliniska studier;

    Abstract : Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating events. READ MORE

  4. 2. Microvascular brain raspberries: A clinicopathological study

    Author : Henric Ek-Olofsson; Lund Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebrovascular disease; cerebral small vessel disease; vascular dementia; neurodegenerative disease; frontotemporal lobar degeneration; hypertension;

    Abstract : .... READ MORE

  5. 3. Measurable residual disease and clonal evolution in acute myeloid leukemia with focus on NPM1-mutations

    Author : Louise Pettersson; Lund Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AML; MRD; Measurable residual disease; NPM1; NPM1-mutation; NPM1 type A mutation; clonal evolution; clonal patterns; subclones; genetic evolution; qPCR; RQ-PCR; ddPCR; deep seq; deep sequencing; NGS; RT-qPCR; old; elderly; MFC; flow cytometry;

    Abstract : Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with mutations in the NPM1 gene occurring in almost one third of all cases. The ability to detect residual leukemia below the resolution of conventional microscopy is crucial for evaluation of relapse risk after therapy. READ MORE

  6. 4. Cyclin A1 Expression and Regulation in Hematopoietic and Leukemic Cells

    Author : Jenny Ekberg; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; onkologi; Cytologi; cancerology; oncology; Cytology; AML; cyclin A1; apoptosis; cell cycle regulation;

    Abstract : Increased expression of the cell cycle regulatory protein cyclin A1 has previously been detected in patients with acute myeloid leukemia (AML) and targeted overexpression of cyclin A1 in a transgenic mouse model initiated AML. The aim of this thesis was to further study the expression and regulation of cyclin A1 in hematopoietic cells. READ MORE

  7. 5. Proliferation, Invasion and p16 Localisation in Malignancies

    Author : Kristina Nilsson; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Cytologi; cancerology; Cytology; oncology; skin tumours; invasion; p16; cancer; patologisk anatomi; Patologi allmän ; pathological anatomy; proliferation; General pathology;

    Abstract : Uncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. READ MORE