Search for dissertations about: "Lung cancer therapy"

Showing result 1 - 5 of 79 swedish dissertations containing the words Lung cancer therapy.

2. 1. Angiogenesis Related Markers In Non-Small Cell Lung Cancer

   Author : Daniel Brattström; Ola Brodin; Gunnar Wagenius; Torgny Rasmusen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; NSCLC; Therapy; Angiogenesis; VEGF; bFGF; Microvessel density; Survival; Onkologi; Oncology; Onkologi;

   Abstract : This thesis investigated the predictive and the prognostic powers of angiogenesis related markers in both operable and inoperable non-small cell lung cancer (NSCLC) patients.In the first and second study, we investigated the serological fractions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in 2 cohorts of patients with either operable or inoperable NSCLC. READ MORE

4. 2. Improving the diagnostic armamentarium of lung cancer

   Author : Hedvig Elfving; Patrick Micke; Fredrik Pontén; Marika Nestor; Reinhard Büttner; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; tissue microarray; immunohistochemistry; targeted therapy; immunotherapy; checkpoint inhibitors; immune microenvironment; prognosis; biomarkers; immune cells.;

   Abstract : Lung cancer is the leading cause of cancer-related death globally, with non-small cell lung cancer (NSCLC) constituting 85% of cases. The introduction of immunotherapies and targeted therapies have dramatically improved the prognosis and outcome for a subset of patients, and stressed the development of diagnostic tools for effective patient selection. READ MORE

5. 3. Long-term effects of adjuvant tamoxifen treatment on cardiovascular disease and cancer

   Author : Johan Rosell; John Carstensen; Olle Stål; Bo Nordenskjöld; Lars Holmberg; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adjuvant; adverse events; breast cancer; cerebrovascular disease; coronary heart disease; heart failure; lung cancer; second primary cancer; tamoxifen;

   Abstract : The aims of this thesis were to investigate the long-term effects of adjuvant tamoxifen treatment on breast cancer recurrence and mortality, cardiovascular disease, and the incidence of secondary cancer.Between 1982 and 1992, postmenopausal patients with early stage breast cancer were included in a randomized clinical study of 2 or 5 years of postoperative tamoxifen therapy. READ MORE

6. 4. The role of phosphatidylinositol 4-phosphate 5-kinase type І alpha (PIP5K1α) and utility of its inhibitor for targeting metastatic cancer

   Author : Martuza Sarwar; Malmö Experimentell cancerforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate Cancer; Breast cancer; Cancer therapy; PIP5K1A; PI3K AKT signal pathway; Kinase inhibitors;

   Abstract : Prostate cancer (PCa) is the most common cause of cancer-related death in men after lung cancer. Annually, more than 9000 new cases are diagnosed in Sweden and 2500 of them die each year. Metastatic prostate cancer can be treated with castration. READ MORE

7. 5. Genomic characterization of non-small cell lung cancer - clinical and molecular implications

   Author : Anna F Karlsson; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung cancer; histology; non-small cell lung cancer; gene expression; gene fusion; Methylation;

   Abstract : Lung cancer accounts for 1.6 million cancers annually and 1.3 million deaths per year make the disease the deadliest type of cancer. Smoking is the most prominent cause. READ MORE