Search for dissertations about: "Lung fibroblasts"

Showing result 1 - 5 of 41 swedish dissertations containing the words Lung fibroblasts.

  2. 1. Models of alveolar remodeling in chronic lung disease

    Author : Oskar Rosmark; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix ECM ; Decellularization; Mass Spectrometry MS ; Biomechanics; Chronic obstructive pulmonary disease COPD ; Idiopathic pulmonary fibrosis IPF ; Alveolar epithelial cells; Fibroblasts; Lung slices;

    Abstract : Lung function is highly dependent on the structure of the lung parenchyma. Remodeling of the alveolar compartment is a central part of the pathology of chronic lung disease such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). READ MORE

  4. 2. Effects of Asthma Combination Therapy on Extracellular Matrix Remodeling in Human Lung Fibroblasts

    Author : Lizbet Todorova; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Proteoglycans; Lung fibroblasts; Collagen; Airway remodeling; TGFβ; Glucocorticoids; Combination therapy.; β2-agonist; MMPs;

    Abstract : Fibroblasts, being one of the resident and structural cells of the lung, have the capacity to produce inflammatory mediators, cytokines and extracellular matrix (ECM) proteins perpetuating the inflammation in the airways of asthmatics. Airway remodeling is also a prominent feature of asthma that affects the lung function causing a thickening of the airways. READ MORE

  5. 3. Mesenchymal heterogeneity in the adult human lung

    Author : Måns Kadefors; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung; Extracellular matrix; Adventitia; Fibroblast; mesenchymal cell; Alveolar epithelial cell; Fibrosis; Idiopathic pulmonary fibrosis; Mass spectrometry; RNA-sequencing;

    Abstract : The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. READ MORE

  6. 4. Mast cells and its crosstalk with mesenchymal cells in chronic lung diseases

    Author : Mariam Bagher; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Fibroblasts; IPF; COPD; Extracellular matrix; Remodelling; Inflammation; Tryptase; Chymase; Protease-activated receptor 2; Migration;

    Abstract : .... READ MORE

  7. 5. Stress Response in Chronic Obstructive Pulmonary Disease - Effect of Cigarette Smoke Extract and Hypoxia on Structural Lung Cells

    Author : Martin Garcia-Ryde; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; Cigarette smoke extract CSE ; Lung fibroblasts; Hypoxia; Gene expression;

    Abstract : Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide according to the world health organization. It is a disease characterized by chronic inflammation and emphysema, and cigarette smoking is the main cause of COPD development. READ MORE