Search for dissertations about: "Lymphangiogenesis"

Showing result 1 - 5 of 16 swedish dissertations containing the word Lymphangiogenesis.

  1. 1. Lymphangiogenesis and lymphatic metastasis

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Meit A Björndahl; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; lymphangiogenesis; lymphatic metastasis; PDGF; IGF; VEGF-A;

    Abstract : The major cause of cancer mortality is metastasis, which relies on the growth of blood vessels (haemangiogenesis) and lymphatic vessels (lymphangiogenesis). Whereas the field of haemangiogenesis has been relatively thoroughly studied, little is known about the mechanisms regulating lymphangiogenesis. READ MORE

  2. 2. Molecular and Biological Characteristics of Stroma and Tumor Cells in Colorectal Cancer

    University dissertation from Linköping University Electronic Press

    Author : Jingfang Gao; Linköpings universitet.; Linköpings universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carcinogenesis; genetic alterations; colorectal cancer CRC ; cysteine-histidine rich protein PINCH ; Inflammatory infiltration; Angiogenesis; lymphangiogenesis; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi;

    Abstract : Carcinogenesis is a progressive process involving multiple genetic alterations in tumor cells and complex interactions in the tumor-host microenvironment. To better understand the contribution of molecular alterations in tumor cells and stromal variables to the development of colorectal cancer (CRC) and identify prognostic factors, in this study we examined the clinicopathological and biological significance of stromal variables, including particularly interesting new cysteine-histidine rich protein (PINCH), inflammatory infiltration, angiogenesis and lymphangiogenesis, as well as hRAD50/hMRE11/hNBS1 proteins and hRAD50 mutation in tumor cell in CRC. READ MORE

  3. 3. Invasive and Metastatic Properties of Advanced Prostate Cancer

    University dissertation from Linköping University Electronic Press

    Author : Karin Jennbacken; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

    Abstract : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. READ MORE

  4. 4. Hypoxia, PDGF and VEGF in Vascular Development

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ingrid Nilsson; Uppsala universitet.; [2006]
    Keywords : Cell biology; hypoxia; VEGF; VEGFR-3; PDGF; endothelial cell; embryonic stem cell; angiogenesis; lymphangiogenesis; Cellbiologi;

    Abstract : The mechanisms behind many important aspects of blood- and lymphatic vessel formation have yet not been elucidated in detail. The primary objectives of this thesis have therefore been to study the effects of hypoxia, platelet-derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs) on vascular development and function. READ MORE

  5. 5. Hem- and lymph-angiogenesis in cancer metastasis

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Hong Ji; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Angiogenesis, the process of sprouting new microvessels from the preexisting vasculature, is known to promote tumor growth. However, the role of tumor angiogenic vessels in facilitating metastasis remains poorly understood. READ MORE