Search for dissertations about: "Lymphatic system"

Showing result 11 - 15 of 30 swedish dissertations containing the words Lymphatic system.

  2. 11. Superparamagnetic iron oxide nanoparticles (SPIONs) as a multimodality imaging probe for sentinel nodes : Design and Preclinical Evaluation

    Author : Renata Madru; Lund Medicinsk strålningsfysik; []
    Keywords : iron oxide; nanoparticles; SPIONs; PET-MRI; SPECT-MRI; SPECT-MRI- optical imaging; sentinel lymph node; SNL;

    Abstract : Breast cancer and malignant melanoma disseminate through the lymphatic system and the first metastases arise in one or two regional, sentinel lymph nodes (SLNs) draining the primary tumour site. Therefore, identification and characterization of the SLNs is of major importance for cancer staging and for choice of therapy in patients. READ MORE

  4. 12. Neoadjuvant chemotherapy in muscle-invasive urinary bladder cancer : studies on treatment response, tumor draining lymph nodes and blood transfusion

    Author : Robert Rosenblatt; Amir Sherif; Ola Winqvist; Per Marits; Ralph Peeker; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bladder cancer; neoadjuvant chemotherapy; tumor downstaging; sentinel nodes; blood transfusion; Urology; kirurgi; särskilt urologi; Medicine; medicin;

    Abstract : Muscle-invasive urinary bladder cancer is a deadly disease. Mortality rates remained unchanged for decades despite radical surgery.After several randomized trials, we today know that cisplatin based chemotherapy given prior to cystectomy, improves survival for every tenth patient. READ MORE

  5. 13. Mechanisms of malignant and non-malignant angiogenesis using zebrafish models

    Author : Lasse Dahl Ejby Jensen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pathological angiogenesis significantly contribute to the onset, development and progression of most common and severe human diseases including cancer, metastatic disease, cardiovascular disease, age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity. Under these pathological conditions, tissue hypoxia often acts as a trigger to switch on angiogenesis. READ MORE

  6. 14. Exploring immunotherapeutic targets in the tumor microenvironment

    Author : Anna-Maria Georgoudaki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system has developed along with the evolution of increasingly complex cellular organisms to sustain homeostasis and protect from threats. Cancer, a detrimental side effect of increasing organismic complexity, typically sequesters the immune system and hijacks its functions for its own prosperity. READ MORE

  7. 15. Multimodal sentinel lymph node imaging using nanoscale-tailored particles; The importance of particle size

    Author : Pontus Kjellman; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multimodal contrast agent; USPIO; sentinel lymph node; in vivo; EL-4 tumor;

    Abstract : As a cancer grows it will, at a certain stage of disease progression, start spreading in the body. For several types of cancer this spreading will first occur through the lymphatic system and the first place where metastatic cell will be encountered is the first lymph node that drains the area where the tumor is located. READ MORE