Search for dissertations about: "Lymphoid malignancies"
Showing result 6 - 10 of 53 swedish dissertations containing the words Lymphoid malignancies.
-
6. Genetic changes in lymphoid leukemia
Abstract : It is today generally accepted that the vast majority of malignant tumors arise as a result of genetic changes in critical genes involved in the tightly regulated control of cell growth and cell death. Despite the remarkable progress in the identification of such genes during the past two decades, many cancer genes probably remain to be identified. READ MORE
-
7. Targeted CD52 therapy in lymphoid malignancies : a clinical and immunological study
Abstract : There is a great need for developing new treatment alternatives in low grade non Hodgkin's lymphoma (NHL) including chronic lymphocytic leukemia (CLL). The CD52 antigen, which is expressed on almost all lymphoid malignancies, can be utilized as a target for CD52-directed monoclonal antibody therapy (alemtuzumab, Campath-1 H). READ MORE
-
8. Genetic changes in childhood acute lymphoblastic leukaemia and other lymphoid malignancies
Abstract : Malignant transformation of normal cells is the result of defects in cell growth control, differentiation and programmed cell death. It has been convincingly shown that malignant cells carry mutations in the genes controlling these cellular processes. READ MORE
-
9. Alterations of the short arm of chromosome 9p in lymphoid malignancies
Abstract : Malignant disease evolves through the successive accumulation of genetic lesions affecting growth-controlling genes in the cell-clone undergoing malignant transformation. 9p21 has long been suspected to harbour a tumour suppressor gene, because of frequent deletions of this region in malignancies including acute lymphocytic leukaemia (ALL). READ MORE
-
10. Ploidy, cell proliferation and apoptosis in lymphoid malignancies : methodological and clinical aspects
Abstract : The DNA aneuploidy and proliferative activity have been previously shown to carry a clinical significance in Iymphoid malignancies. However, the application of these parameters is complicated by methodological difficulties. READ MORE