Search for dissertations about: "M D A"

Showing result 6 - 10 of 486 swedish dissertations containing the words M D A.

  2. 6. Risk-Adjustment for Swedish In-Hospital Trauma Mortality using International Classification of disease Injury Severity Score (ICISS) : issues with description and methods

    Author : Robert Larsen; Folke Sjöberg; Ingrid Steinvall; Mats Fredrikson; Sten M. Walther; Søreide Eldar; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : IntroductionDifferent methods have been used to describe the epidemiology of trauma with varying results. Crude mortality outcome data differ significantly from risk-adjusted information. A previous standard method for risk-adjustment in trauma was the Injury Severity Score (ISS), although it has several shortcomings. READ MORE

  4. 7. Neuron-to-neuron propagation of neurodegenerative proteins; relation to degradative systems

    Author : Jakob Domert; Martin Hallbeck; Jan Marcusson; Lars Tjernberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell-to-cell transfer; beta-amyloid; Alzheimer s disease; degradation; proteasome; alpha-synuclein; Parkinson s disease; high throughput screening model;

    Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are defined by neurodegeneration and accumulations of misfolded proteins that spread through the brain in a well characterized manner. In AD these accumulations consist mainly of β-amyloid (Aβ) and tau, while in PD, α-synuclein (α-syn) make up the characteristic lewy pathology. READ MORE

  5. 8. The Social World Through Infants’ Eyes : How Infants Look at Different Social Figures

    Author : Clara A. Schmitow; Gunilla Stenberg; Gustaf Gredebäck; Annika M.D. Melinder; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; infant social looking; emotional facial expressions; experience; identity; behavior regulation; head-mounted cameras; eye-tracking; Psychology; Psykologi;

    Abstract : This thesis aims to study how infants actively look at different social figures: parents and strangers. To study infants’ looking behavior in “live” situations, new methods to record looking behavior were tested. Study 1 developed a method to record looking behavior in “live” situations: a head-mounted camera. READ MORE

  6. 9. “Dr Jekyll and Mr Hyde?” : Abuse of potent benzodiazepines, exemplified by flunitrazepam, in mentally disordered male offenders

    Author : Anna Maria Dåderman; Marianne Kristiansson; Lars Lidberg; Ann Wirsén Meurling; Sten Levander; Fred Nyberg; Karolinska Institutet Division of Forensic Psychiatry Department of Clinical Neuroscience; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Flunitrazepam FZ abuse; side effects of FZ; offenders referred to forensic psychiatric evaluation; juvenile delinquents; personality traits; psychopathic traits and lifestyle PCL-R ; Psychology; Psykologi; Flunitrazepam FZ abuse; side effects of FZ; offenders referred to forensic psychiatric evaluation; juvenile delinquents; personality traits; psychopathic traits and lifestyle PCL-R .;

    Abstract : Flunitrazepam (FZ) is an example of a sedative-hypnotic benzodiazepine whose pharmacokinetic properties include a rapid onset of action and an intermediate duration of action. It has a high affinity to central benzodiazepine receptors and affects them profoundly. READ MORE

  7. 10. Advances for Biomarker Discovery in Neuroproteomics using Mass Spectrometry : From Method Development to Clinical Application

    Author : Marcus O.D. Sjödin; Magnus Wetterhall; Jonas Bergquist; Dominic M. Desiderio; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Biomarker; Proteomics; Central Nervous System; Cerebrospinal Fluid; Traumatic Brain Injury; Cloud-Point Extraction; Neuroproteomics; Relative Quantification; Spinal Cord Stimulation; Neuropathic Pain; Analytical Chemistry; Analytisk kemi;

    Abstract : Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used as biomarkers for early diagnosis, assessing treatment or drug development. Clinical proteomics aim to screen for protein biomarkers by a comprehensive analysis of all proteins expressed in a biological matrix during a certain pathology. READ MORE