Search for dissertations about: "M-proteins"

Showing result 6 - 10 of 23 swedish dissertations containing the word M-proteins.

  2. 6. Induction and functional role of type I interferon in bacterial infection of macrophages

    Author : Elin Movert; Infektionsimmunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophage; Streptococcal M proteins; Mycobacterium marinum; Type I interferon; Infection;

    Abstract : Infection represents an evolutionary arms race between pathogen and host. Thus, scientists find that pathogenic microbes have evolved elegant strategies to manipulate or avoid our immune system, allowing them to persist within the human population. READ MORE

  4. 7. Resistance to phagocytosis in Streptococcus pyogenes

    Author : Fredric Carlsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; Medicine human and vertebrates ; Medicin människa och djur ; phagocytosis; innate immunity; complement; Streptococcus pyogenes; M protein;

    Abstract : Phagocytosis of Streptococcus pyogenes is complement dependent. However, the cell wall-associated M protein, which exists in >100 different serotypes (M types), enables the bacteria to evade phagocytosis. READ MORE

  5. 8. Mechanisms of phagocytosis resistance in Streptococcus pyogenes

    Author : Heike Kotarsky; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; fibrinogen; FHL-1; Factor H; M protein; Streptococcus pyogenes; phagocytosis;

    Abstract : A distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and fibrinogen that plays a key role in coagulation. READ MORE

  6. 9. Studies of bacterial surface proteins interacting with the immune system

    Author : Henrik G Svensson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; Mikrobiologi; virologi; mykologi; Microbiology; bacteriology; virology; mycology;

    Abstract : Pathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. READ MORE

  7. 10. Interactions of human C4BP with Bordetella pertussis and Streptococcus pyogenes

    Author : Karin Berggård; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; antigenic variation; phagocytosis resistance; complement; C4b-binding protein C4BP ; Bordetella pertussis; Streptococcus pyogenes; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Many microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. READ MORE